Harmful algal blooms: Links between lake ecology, chemistry, and drinking water treatment

Overall project:
Human activities can profoundly alter aquatic ecosystems and create major challenges for the provision of safe drinking water. For example, high nutrient loads can dramatically increase algal productivity. This in turn can alter lake chemistry and ecology, which can have significant effects on water treatment processes. Ecological changes can include the occurrence of harmful algal blooms. An increase in the frequency and severity of algal blooms is a major concern across Canada and globally.

Incidence, pathogenesis and control measures of Enterococcus infections in chicken embryos and neonatal broiler chickens (New)

Yolk sac infections have become the number one disease problem in the broiler chicken industry in Canada.
The emergence of yolk sac infections due to Enterococcus species has increased over the last two years at
poultry hatcheries in Saskatchewan and as a result, chick quality and broiler performance have decreased
significantly.

Customary International Law Norms on Indigenous Rights in Comparative Case Law

This research project is part of a larger research programme on Indigenous rights in constitutional and international law. Within this particular project, the faculty member is examining decisions of different domestic courts that bear on customary international law on Indigenous rights.

Hydrotreating of heavy gas oil using mesoporous materials supported NiMo catalysts

The sulfur and nitrogen containing compounds present in crude oil, needs to be removed before downstream catalytic processing of crude oil because (i) sulfur is known to be poisonous for catalyst and (ii) to meet stringent environment regulations. The most widely used process for sulfur and nitrogen removal is hydrotreating. Hydrotreating is a catalytic process at high temperature of 350-400 °C and moderate pressures of 1200-1400psi. The conventional catalyst used for hydrotreating is Ni or Co and Mo or W supported on .-Al2O3. The majority of petroleum reserves in Canada are in Oil sands.

Imaging Processing and Machine Learning in Clinical Microscopy

In many clinical laboratory and pathology testing procedures, visual examination of microscopic slides is needed, e.g., to classify disease developments, to detect the interactions of micro-organisms, to assess the effectiveness of drugs, to determine cell viability and proliferation, etc. These tasks can be found in many important clinical applications, including cancer research, hematology, pharmacology, and genetic testing.

Traditionally, these tasks are performed manually by a qualified laboratory technician.

Structural and Functional Investigation of Disrupted in Schizophrenia 1 (DISC1)

The research project involves investigating the structure and function of DISC1 subdomains. As DISC1 is a large protein with multiple functions, breaking it down into its subdomains will facilitate our understanding of its biology. The biochemical and biophysical properties of subdomains will be characterized. This 12-week project will allow the student to learn how to use a state-of-the-art protein chromatography system to produce large quantity of proteins needed for downstream structural biological investigation.

Comparison of winter limnology between selected reservoirs in Saskatchewan

Lakes across much of Canada are ice-covered for long periods every year. Ice cover creates conditions fundamentally different from other seasons, with low light penetration, low temperatures, and the presence of a barrier to gas exchange. Climate change predictions suggest that reductions in ice cover can be expected. However, logistical challenges associated with winter field work mean that we have relatively poor understanding of current conditions in lakes during winter.

Developmental genetics of the zebrafish skeleton

Osteoarthritis is a major obstacle to work productivity and quality of life for many Canadians, affecting over 10% of the general population and 15% of Saskatchewanians, with the elderly increasingly affected (>40% of Canadians over 65 years old). At the cellular and molecular level, osteoarthritis involves two main defects: 1) degradation of sugar-coated proteins (proteoglycans) in the cartilage that protects bones at the joints, and 2) changes to gene expression in the cells (chondrocytes) that maintain cartilage.

Exercise and a flax nutritional supplement for reducing blood pressure in older individuals

The purpose of the research project is to determine the effects of a flax-based nutritional supplement and an exercise program (walking) for improving blood pressure in older individuals. Both of these interventions lower blood pressure and we want to determine whether their effects are additive for reducing blood pressure. We will evaluated blood pressure with 24-hour monitors and also assess blood markers for cardiovascular disease risk.

Development of Pickering water-in-oil-in-water double emulsion delivery system for protection of labile bioactive compounds

We recently showed that the fat crystal shells around water-in-oil (W/O) emulsion droplets could effectively screen the hydrophilic active components from the outer environment (Ghosh et al., Salt Release from Fat Crystal-Stabilized Water-in-Oil Emulsions. 103rd AOCS Annual Meeting, Long Beach, California, USA, May 2012). Formation of crystal shells around dispersed droplets in emulsion is a novel stabilization mechanism in which fat crystals or other suitably surface-active particles absorb on the droplet surface thereby providing a physical barrier to coalescence.

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