The Epidemiology of Fabry Disease and Metabolic Acidosis in Manitoba

The proposed project is for the postdoctoral fellow to access healthcare data for individual adults in the province of Manitoba in order to: 1) determine the rates of metabolic acidosis in Manitoba along with associated outcomes and risk factor profiles and 2) identify patients in Manitoba who are at high risk of Fabry disease but currently undiagnosed in order to facilitate disease screening and improve patient care.

Modelling the impact of water pressure on water main breaks using a spatially explicit Bayesian model

Providing safe drinking water to the population is one of the main roles of municipalities. However, due to aging urban infrastructure, the number of pipe break is an increasingly around the world which is costly at the economic, social and environmental levels. Municipalities need to have tools that allow predicting these breaks so they can develop a preventive strategy to repair or replace vulnerable pipes before they break. This project proposes to use modern statistical tools to create a model that will use water pressure and pipes characteristics to predict pipe breaks.

Benzodiazepine and Opioids Use in Alberta

Opioids have received much attention in the media, public and government because of the risks associated with them, including fatalities. Concurrent use of BZRAs (benzodiazepines used for treating anxiety and insomnia) and opioids is of particular concern because this is a recognized risk factor for fatal opioid overdoses. Despite this warning, concurrent use is still occurring. An outcome study using Alberta data on concurrent use has not been published in the literature.

Mobilizing Ulukhaktok Traditional Knowledge of the Dolphin and Union Caribou Herd

The Dolphin and Union caribou herd is integral to Inuit culture, subsistence and identity. Preliminary local and scientific knowledge both indicate that this caribou herd is declining and in poorer health than before. We need to bring everyone together and use everything we know about Dolphin and Union caribou, the environment and the other animals to help protect and care for these animals.

Preventing medication errors in patients with low kidney function.

Patients with low kidney function need to take certain medications at a lower dose because their kidneys cannot filter the medication as well from the body. Taking medications at a high dose may be harmful to a patient and lead sometimes to death. The aim of my research is to help reduce medication errors in patients with low kidney function. I will do this by conducting several large studies to determine optimal medication dosing for patients with low kidney function.

Development of a clinical protocol for the validation of a detection test for ??amyloid aggregates in retinal scan images.

Alzheimer’s disease (AD) is a neurodegenerative disorder that is difficult to detect early before apparent manifestations of cognitive decline. Current detection methods rely on expensive and hardly accessible imaging techniques (PET scans). Optina Diagnostics developed a new camera as well as innovative image processing methods to propose a non-invasive test to identify the presence of AD biomarkers in evaluated individuals. The objective of this collaborative effort is to develop a clinical protocol to test this new technology.

Preference analyses and development of an e-health app facilitating communication of test results for hereditary cancer syndromes

An estimated 5-10% of cancers are inherited through family members. To identify patients’ risk for developing hereditary cancers, genetic testing can be used. Communicating hereditary cancer genetic results to patients is challenging for health care practitioners. Practitioners want to ensure that patients understand and communicate their preferences for receiving information. Tools to aid patients in communicating their preferences need to be developed.

Tracing the Historical Plays of Power in Alberta’s Recreation System

When we research the knowledge of the past, we also research the conditions of possibility for different futures (Foucault, 2003; Peers, 2015). Therefore, the purpose of this research project is to use the traces of the past to question the practices that have come to be naturalized within Alberta’s recreation system (e.g., providing pay-per-use recreation opportunities in big box facilities). Using an intensive archival research process, as well as a series of ongoing community conversations, we hope to uncover what is problematic and dangerous in recreation’s practices and discourses.

The Voices of Children and Youth: Community Injury Prevention through Visual Storytelling and Intervention (VOICES) in First Nations communities

The Voices research project aims to build injury prevention capacity within the First Nation community of Akwesasne (near Cornwall, ON) and among researchers.

Canadian Communities of Practice in Global Health: meeting the SDG challenge - Year two

Canada’s commitment to the Sustainable Development Goals (SDGs) has implications for both domestic and foreign policy in a complex, shifting, and interdependent global health system crowded with multiple actors and stakeholders. The array of activities involved with global public health practice necessitates engagement with health policy and systems research (HPSR), and Knowledge Translation (KT) is critical to bridging the gap between knowledge generated through research and the knowledge that is used to inform policy, practice, and programs.

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