Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic subjects. However, the mechanism of action of the peptide treatment is still not fully understood.

Ergonomic Design of an Automotive Material Sequencing Centre - Year two

The Ford Motor Company is bringing 800 jobs into the Oakville Assembly Plant. These jobs will be concerned with sequencing parts for the new Material Sequencing Centre. To ensure that workers remain healthy, and their
productivity and quality output is up to Ford's high standards, Ford (through this fellowship) wants to establish clear ergonomic guidelines for this type of work. The post-doctoral fellow will conduct surveys in the plant, as well as review existing ergonomic guidelines within Ford.

Development of a Self-Regulatory App for Adults with Celiac Disease

Celiac disease is an autoimmune dysfunction that requires strict adherence to a gluten-free (GF) diet in order to prevent detrimental health outcomes. Following a strict GF diet is difficult given that gluten is added as a preservative or binding agent to many foods. Findings from a review suggest strict adherence to a gluten-free diet is as low as 42%. As such, poor adherence to a GF diet is an emerging health concern for people living with celiac disease.

Healthy Obesity through Fitness

Rates of obesity are continuously rising despite efforts to decrease them. The purpose of this study is to show that obese but fit individuals are protected from many adverse health conditions such as metabolic syndrome, insulin resistance, type-2 diabetes, high blood pressure, and cardiovascular disease as the result of being physically active. This study is designed to assess, independently, the contributions of cardio-respiratory fitness (CRF) and adiposity to the metabolic health of obese individuals.

Optimizing track cycling performance through neuromechanical measurement and modelling

Current performance optimization models of track cycling are inadequate to estimate conditions such as the start of the race and during positional changes of the athletes. Monitoring muscle excitation is a valuable way to quantify metabolic changes since it does not discriminate the energy source. Muscle excitation is therefore a good parameter to explore the influence of the energy utilization aspect of model predictions.

Strengthen Your Health: Interdisciplinary Intervention Program for Promoting an Active and Healthy Lifestyle Among Students

There are a number of factors that can impact ones level of physical activity. Interpersonal, intrapersonal, and environmental factors are all important when looking at how active or sedentary an individual can be. For schoolchildren, it is important to promote active behaviors that will lead to a healthy lifestyle. By creating a tool to identify factors that influence sedentary behaviors, it can help to promote interventions to encourage students to be more active and more fit.

Facilitators and Barriers to Knowledge Translation for Diabetes Management in Mexican Health Units

Type 2 Diabetes (T2D) is a major cause of death worldwide (“WHO | The top 10 causes of death,” 2014). In Mexico, high incidence rates of diagnosed T2D (9.2%) and obesity (34.4%) pose a burden for the health system (Instituto Nacional de Salud Publica (INSP), 2012b). A national strategy for diabetes management, the Grupos de Ayuda Mutua (GAM), has been implemented, in response to rising T2D rates. Individual GAMs consist of peer-support and education and clinical attention by a health care team.

Innovative Game-Based Rehabilitation Platform for children with motor and cognitive impairments due to neuro-developmental disorders and acquired brain injuries

We have developed an innovative computer-aided, game-based platform for rehabilitation. The platform includes an embedded automated assessment subsystem, which provides electronic measures of fine and gross motor skills and specific psychomotor skills. The primary objective of this research project is to evaluate the test-retest reliability and convergent validity of the standardized assessment subsystem embedded into our game-based rehabilitation platform.

Scientific Validation of the CBI Workplace Solutions Pre-Placement Functional Assessment for Canada Post Delivery Agents

The purpose of this project is to conduct a scientific evaluation of pre-placement functional assessment for Canada Post delivery agents. Within the project, the research team will evaluate how delivery agents (letter carriers) perform mocked-up work tasks (based on actual job tasks observed in the field). Then the research team will evaluate how delivery agents perform the pre-placement functional assessment.

Optimizing the use of blood flow restriction for pre-conditioning & recovery of human performance

I am exploring the use of restricting blood flow from muscles (using a tourniquet or blood pressure cuff) to better prepare an athlete’s body for competition. This technique, known as ischemic preconditioning (IPC), has demonstrated enormous potential for improving the performance of already well-trained athletes. Preliminary work has shown a 1-3% improvement in performance in elite athletes, a 2.5% improvement would have placed the 8th place finisher 1st in the famous 100m butterfly final in the 2012 Olympics.

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