Brain to Machine Interface Based on EEG Signals

Brain to machine interface (BMI) is a research topic aiming to develop more direct interface between a human brain and a machine. The research is primarily motivated by desire to help humans who are in need of assistance or repair of their

Analysis of cost of international public health interventions

There are two sets of literature estimating the cost of health interventions in different countries.However, actual program cost data are not available for all programs (whereas it is easier to generate estimates using the “ingredients approach”).  In this project, we will undertake a literature review to match actual program costs to those predicted by the ingredients approach, for a range of public health interventions.  We will then utilize this to try to generate some systematic patterns and observations as to the relationship between the two methods.  The aim would be to write a publis

Determination of vessel wall shear stress in the cerebral vasculature using magnetic resonance imaging and computational fluid dynamics

Our project consists of a combination of magnetic resonance imaging (MRI) and numerical simulations to model the blood flow dynamics in major cerebral arteries. In doing so, we hope to determine the shear stresses that are inflicted on the vessel walls of the brain, which should correlate with the vessel’s ability to dilate in response to a vasoactive stimulus. This autoregulatory effect can be measured in terms of cerebrovascular reactivity and is shown to be a useful biomarker for cerebral disease.

Non-human adenoviruses as vaccine delivery vehicles

Infectious diseases remain the major cause of death and economic losses in animals/humans. One way to reduce this is by vaccination. Unique and sophisticated biotechnology-based approaches are needed to produce safe, cost-effective, and highly efficacious vaccines. Potential benefits of these vaccines could include the induction of long lived immunity, ability to immunize newborns and induction of a broad spectrum of immune responses. One way to achieve this is to develop live viral vectored gene

Structure and Function of a Ribonucleoprotein Particle

The Kothe research group studies the structure and function of small ribonucleoproteins which are involved in ribosome biogenesis, in particular in modification of ribosomal RNA, with the aim of better understanding how the cell assembles large RNAprotein complexes such as the ribosome.