When light interacts with matter, different effects may take place, depending on the particular characteristics of both light and matter. The result of this interaction, typically a quantitative change in the characteristics of the light (i.e., intensity, wavelength, phase), can be used to measure the presence of a particular specimen of interest. Specifically, Surface-enhanced Raman Scattering (SERS) has demonstrated to be able to detect accurately very low concentrations of chemical species.