A Novel Radiofrequency Treatment for Emphysema in Pig Model

A common condition that contributes to Chronic Obstructive Pulmonary Disease (COPD) is emphysema, which involves damage to the walls of air sacs in the lung. There are very limited safe and non-invasive options available, therefore IKOMED Technologies Inc. has been developing an application using radiofrequency wave technology that has shown the potential to non-surgically improve disease burden. The initial study was performed in the rodent model of emphysema with Dr. Don Sin, and study in larger animals is important for translation to clinical use.

Understanding juvenile salmon passage at newly created breaches in two major barriers in the Fraser River estuary, BC.

Estuaries are crucial stopover areas for juvenile salmon during outmigration and especially for Chinook salmon who can reside in this habitat for over a month. Many populations of Chinook salmon from the Pacific Northwest are threatened and endangered making conservation important for this species. Currently, managers are investing significant public funds in estuary restoration and understanding the effectiveness of these investments is crucial to recovery of many salmon populations.

Fingerprinting favourable volcanic horizons for precious and critical metal deposits in the Golden Triangle, British Columbia

This project will help determine the history and distribution of the volcanic rocks which hose important copper, gold and critical metal deposits in the so-called “Golden Triangle” of NW British Columbia. The interns involved will apply various methods to determine the age, chemical composition and distribution of the Jurassic age volcanic rocks of the Hazelton Group. The interns will spend time in the field with their partners, and spend time at the University of British Columbia generating key supporting data sets in the UBC laboratories in the Mineral Deposit Research Unit.

Model systems to Assess The in vitro efficacy of CFTR modulator tHerapies in Cystic Fibrosis (MATCH-CF)

Cystic fibrosis (CF) is a genetic disease is caused by changes (mutations) in a gene that produces a protein called the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is responsible for salt transport and when it does not work properly it leads to organ dysfunction. A new generation of therapies are now available that improve function of the CFTR protein and are known as CFTR modulators and they have contributed to improving the lung function and the quality of life for people living with CF (PwCF).

Automated high-throughput characterization of microbiome composition and diversity

The mineral mining industry in Canada is rapidly shifting toward more sustainable practices that reduce the environmental impacts of extraction, wastewater, and emissions. Although often overlooked, microorganisms, or bacteria, living in the soils and water of mine sites and mining waste materials, collectively known as the ““mining microbiome”, exert strong influence on all stages of the mining life cycle. For example, microorganisms may cause corrosion of equipment via biofouling (corrosion), or be essential to mine cleanup through processes known as bioremediation.

Developing a Sensitive and Quantitative Opioid Detector for Use in a Clinical Setting

The opioid epidemic is a serious health crisis in Canada, North America, and globally and has worsened during the COVID pandemic. Opioid treatment strategies are at the forefront of efforts to tackle this crisis. To improve the replacement therapy currently used, an estimate of tolerance is required. This proposal takes an existing proof-of-concept opioid detection device and adapts it for use in the clinical setting to address this challenge.

Assessment of environmental and economic sustainability of peri-operative patient warming strategies in hospitals

Hospitals use different warming techniques for surgery patients to prevent them from hypothermia, i.e., becoming cold during their operation. Many warming techniques are commonly available and used but studies on their holistic environmental impacts are lacking. The overall environmental impacts and economic costs of products or services can be assessed using life cycle assessment (LCA) and life cycle cost analysis (LCCA), respectively.

Kiln Drying Optimization of Subalpine Fir and Yellow Spruce

For decades, drying sub-alpine fir and yellow spruce is known as an unmanageable task mainly due to the high moisture variation and the presence of wet-wood that result in a broad spread of moisture in kiln-dried timbers. For this reason, a considerable portion of under-dried and over-dried wood can be observed in kiln-dried subalpine fir and yellow spruce. In this research, I will examine whether the final moisture variation could be alleviated by optimizing sorting methods and drying schedules.

Advancing an Intelligent Transportation Data Platform and Environmental Sensing to Promote Sustainable Cities

Transportation services, ranging from public buses to private logistics fleets, could benefit significant from the introduction of Rogers’ 5G wireless networks. This project has a primary objective to support UBC’s efforts to achieve its 2050 emissions reductions goals, with an emphasis on a reduction of GHG and air pollutant emissions from transportation services.

Assessing the ovarian cancer microenvironment with optical coherence tomography and artificial intelligence

Ovarian cancer is one of the deadliest gynaecological conditions in the developed world, as it is often detected late into progression. Efforts to improve surgical and chemotherapeutic approaches have only made marginal improvements to patient outcomes over the past 30 years, but there remains potential within immunotherapeutic approaches. Understanding the tumor microenvironment, and particularly the immune response to cancers and pre-cancers, is critical to selecting appropriate therapies.