Development of soil quality guidelines for use in health risk assessments of contaminated pipeline compressor station sites

Intrinsik has identified a number of key chemical-pathway combinations that are missing environmental quality guidelines but frequently required for evaluating risks at pipeline compressor stations. With support from senior scientific personnel at Intrinsik, the intern will used environmental risk assessments methods to develop risk-based environmental quality guidelines that are relevant to the land use scenario(s) typical of pipeline compressor stations.

Otoscopy and Ophthalmology Training Technology Development

Teaching medical students and allied healthcare professionals accurate and patient friendly diagnosis of ear, eye and nasal conditions are challenging tasks due to the lack of realistic models and interaction with patients. The OONTTDP is a collaboration between the Hospital for Sick Children and Otosim to improve the teaching results through development of realistic simulators with various conditions embedded within an easy to use system.

Novel application of deformable image registration using Computed Tomography for early diagnosis of lung parenchymal disease: focus on lung fibrosis

We aim to optimize advanced Computed Tomography (CT) imaging to provide non-invasive and accurate assessment of early lung fibrosis. Lung fibrosis causes inflammation and scarring of lung tissue and can be progressive, even fatal. Currently, detection of lung fibrosis relies on relatively insensitive tests, such as pulmonary function tests and static lung CT. Alternately, microscopic evaluation of lung cells (histology) can be used but this technique is invasive and provides inconsistent results in disease states that exhibit non-uniform lung involvement.

Intramucosal Lorazepam spray: Whole Cell and Extracellular Eelctrophysiological Study of Pharmacokinetics and Pharmacodynamics

Epileptic patients have a long term risk of recurrent seizures and the mainstay of treatment for controlling seizures is antiepileptic drugs. Management of epileptic emergencies usually requires hospitalization and the administration of intravenous (i.v.) anticonvulsant drugs. Lorazepam i.v. is the most effective treatment of status epilepticus, and therefore is routinely used in hospital emergency departments.

Modelling pollutant removal processes for an underground detention chamber system

This project will determine if underground detention systems provide an equivalent level of service for stormwater treatment as stormwater management ponds. This will be achieved through water quality measurements collected from a StormTrap system and through the development of a pollutant-transfer model. The intern will work with both the Toronto Region Conservation Authority and Con Cast Pipe.

Improving high speed signals of data transmission hardware

Having completed a PhD in Electrical Engineering, Dr. Haleh Vahedi was excited to make new, local connections to advance her career.  During her Mitacs Elevate fellowship, Haleh was supervised by Dr. Tony Chan Carusone of the University of Toronto’s Department of Electrical and Computer Engineering to design an electrical circuit for data transmission at 28 gigabits per second without loss of signal quality or reception.  The circuit she designed could easily be added to existing Snowbush hardware, improving signal integrity without adding complexity to the system.

Advanced investigation of amphoteric reagent-based cyclization of peptides

Encycle Therapeutics is a Toronto-based company that develops new therapeutics for the treatment of autoimmune diseases. Our competitive edge derives from a platform technology that allows for the more efficient synthesis of macrocycle- (ringlike peptides) based therapeutics. This platform involves a proprietary reagent called aziridine aldehyde. This new technique has demonstrated significant potential for the synthesis of macrocycles, however the full utility and versatility as it applies to the development of drug-like compounds has not been fully researched.

A Novel Design of High Temperature Ultrasonic Transducers, Manufacturing, and Testing

The project objective is to design and manufacture ultrasonic sensors capable of operating at temperatures up to 800 oC. Such transducers can be affixed to hot piping systems and pressure vessels in petrochemical plants, electrical power generating stations, and manufacturing plants. These sensors can then provide continuous information to the plant operator regarding the onset of cracks or corrosion in the pipe wall. In addition information related to fluids flowing in the pipe can also be gathered, such as flow rate, fluid temperature, turbulence.

Economic development through sustainable forest management at Haliburton Forest and Wildlife Reserve

Master of Forest Conservation Candidates from the Faculty of Forestry at the University of Toronto will partake in the research and development of biochar in Haliburton Forest and Wildlife Reserve Ltd. Studies will provide a greater basis for certification and standardization of the product for use in forest systems and operations in Haliburton Forest, as well as in urban gardening applications as a soil amendment.