Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce new technology to improve the reliability of protein pharmaceutical characterization.

The intent of this project is to demonstrate the GHG and electricity use savings of a range of low carbon heating, ventilation, and air conditioning (HVAC) technologies in the multi-unit residential building (MURB) sector.
Technologies to be studied include:
• ductless mini-split air source heat pumps (ASHP)
• gas absorption heat pumps
• smart thermostats
As part of a broader program of work that will include long-term performance monitoring studies of these technologies, this MITACS project will involve a qualitative study identifying other barriers presented to the technologies and str

Detecting subtle chemical and physical changes occurring at the early stages of chronic disease and many other infectious diseases caused by harmful bacteria is still a challenge, as ultra-sensitive sensors with large signal-to-noise-ratio are required to detect them. We recently explored new ways to enhance the sensitivity of magnetic nano-sensors and theoretically demonstrated that under optimum design conditions, the sensitivity can be improved by up to a thousand - higher than any of the biosensors currently available on the market.

There is a great need and benefit to integrate artificial intelligence, robotic simulation, and robotics technology into Canada’s medical industry, hospital environment, and healthcare system. Robotic simulation technology, which has been successfully used for space rover missions such as NASA's Curiosity rover and the Mars Pathfinder and Sojourner mission, provides the ability to create and test different types of robots with different hardware configurations, and develop their associated artificial intelligence systems.

This project takes a holistic and comprehensive analysis of all aspects of Success Beyond Limits (SBL’s) programming as well as their research and evaluation frameworks. Operating in a low-income and marginalized setting, youth that attend SBL’s programming find it difficult to find, secure and keep meaningful employment. This research will capture the experiences of those young people coming to SBL’s programs, identify the barriers they face with respect to employment and measure the impact of all of SBL’s programs.

Memory impairment is the most common cognitive complaint among older adults. On the other side of the developmental spectrum, young adults that have been diagnosed with Autism Spectrum Disorders (ASD) have difficulty adapting flexibly to changing social circumstances. These memory and social deficits disrupt every day living. At present, promising interventions based on research using expensive and specialized equipment are reserved for clinical settings.

Wildland fire fighting is a physically demanding public safety occupation. Front-line wildland fire fighters (WFF) must have an appropriate level of job-related fitness for safe and efficient work performance. Beginning in 2011, it was required that all WFF must demonstrate that they are capable of meeting the rigorous physical demands encountered during an initial attack response to a wildland fire. This decision led to the development of the Canadian Physical Performance Exchange Standard for WFF (WFX-FIT).

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results must meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of vaccines and biologics which, relative to small molecular drugs, are more susceptible to contamination by viral or microbial adventitious agents.

The QWeMA division of CANNEX develops solutions for the financial and insurance industry of North America. Our analytics play an important role in determining the value proposition of investment products. Our solutions help the financial community and public through their financial advisors to be able to make informed decisions.
We work at the intersection of finance, mathematics, actuarial science, and computer science. Our solution strategies require us to solve complex mathematical and optimization problems in a finite amount of time.

The objectives of this research project revolve around the emerging world of municipal climate change policy, planning and implementation in an Ontario context. Specifically, this project will:
1. Assess and compare innovative policies and procedures that are being used by Ontario municipalities to integrate growth planning with climate and energy planning.
2. Assess the factors that support and define net zero community building in Ontario.
3.