Engineered Polymers for siRNA Therapy of COVID-19

Coronavirus disease 2019 (COVID-19) has emerged as a major threat to life on earth. COVID-19 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The excessive reaction displayed by immune system against this virus is damaging particularly to lungs, resulting in rapid lung failure and loss of life. We propose to develop a new method to eradicate viral load in COVID-19 patients. We will develop specific drugs and deliver them into lungs in order to stop viral replication, to ease the symptoms of VOCID-19 and cure the disease. The drugs will be formulated in a nanoparticle form and eradicate the virus in infected cells.

Faculty Supervisor:

Hasan Uludag;Ken Cadien

Student:

Amarnath Praphakar Rajendran

Partner:

RJH Biosciences Inc

Discipline:

Chemistry

Sector:

Professional, scientific and technical services

University:

University of Alberta