Left Ventricular Septal Pacing Through Trans-Ventricular Septal Approach – A Feasibility Study

It is well known in Cardiology that chronic right ventricular apex (RVA) pacing (using a pacemaker to regulate heart rhythm by pacing the lower chamber of the heart near the base) might be detrimental to heart function. Right Ventricular Apex (RVA) pacing is the most commonly used for patients. Alternate sites such as right ventricular (RV) pacing, including right ventricular septum and right ventricular outflow tract (RVOT), have not been shown to be definitely superior over RVA pacing. Left Ventricular (LV) pacing alone is more promising and consistently demonstrated significant hemodynamic (blood circulation) benefit over RVA pacing. Traditional LV pacing requires lead placement in the coronary sinus, and activates the LV from the epicardium. However, the procedure is currently more complex and has greater risks. This project will evaluate the feasibility of achieving LV septal pacing and subendocardial LV septum activation using a recently]developed and novel procedure, and also assess its hemodynamic effects.

Faculty Supervisor:

Dr. Stanley Tung


Shantabanu Chakrabarti/Jonathan Man


Providence Health Care




Life sciences


University of British Columbia



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