Salmon peptide identification and purification: insulin modulation

This proposal describes a multidisciplinary approach to optimize the separation of peptides from an enzyme digest of filleting waste (frames) recovered from farm-raised Atlantic salmon. Our work has demonstrated that a particular salmon peptide fraction has the ability to reverse the effects of type 2 diabetes in rodent feeding trials and model system (tissue culture) experiments. We intend to identify the peptide(s) responsible for the bioactivity and to develop a strategy for large scale commercial production. The overall ultimate goal of the team is to develop functional foods/nutraceuticals that contain fish peptides for prevention of type 2 diabetes (T2D) and cardiovascular diseases (CVD) in the Canadian population.

Faculty Supervisor:

Drs. Tom Gill, André Marette, Laurent Bazinet

Student:

Jonathan Rolin, Marion Valle & TBD

Partner:

Discipline:

Engineering - biomedical

Sector:

Life sciences

University:

Dalhousie University

Program: