Improving the clinical oculomotor assessment for patients with multiple sclerosis

Clinicians’ ability to detect abnormal eye-movements has powerful implications for the diagnosis, monitoring of disease progression and evaluation of therapeutic outcomes in patients with multiple sclerosis. Despite the advantages of the oculomotor assessment, standard clinical practices are limited and do not capture the dynamic aspects of eye-movement. Sophisticated methods have been developed in the laboratory […]

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Climate change design adaptation for the next generation of Canada’s masonry systems

In 2018, the results of a Climate Change Adaptation Standards Inventory Analysis conducted by CSA indicated cavity-wall design as requiring urgent climate change adaptation provisions. Distress in cavity-walls is often attributed to excessive differential movements governed by the drying shrinkage of inner loadbearing concrete masonry members, projected to increase with climate change, producing cracks in […]

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Automated technical knowledge curation using machine learning

With the growth of the Internet, the amount of scientific data and information available to research teams has been increasing exponentially in the past two decades, which results in significant information overload. Approaches for manual knowledge extraction and curation does not scale up in practice. The main objective of the project is to create an […]

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Implementation of Photonic AI accelerator system

Al applications require massive computing resources that consume immense energy. Al compute is expected to account for a significant percentage of the global power consumption. As current digital Al chips cannot keep up with demand, more energy-efficient Al chips are required. This project addresses major milestones toward implementing an energy-efficient photonic Al accelerator system. A […]

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Risk-based evaluation and optimization of friction devices for seismic retrofits of non-ductile building structures in Canada

Canada’s early-designed public buildings (i.e., schools and hospitals) are at significant risk of seismic damage and collapse. The installation of seismic protective devices, such as friction devices designed and manufactured by Quaketek Inc, offers a viable strategy to mitigate the seismic risk of building structures. However, the practical use of friction devices has commonly relied […]

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Using high-throughput mapping techniques to reveal mechanisms of vocal learning

Understanding how humans and non-human animals communicate with each other continues to be a central question in neuroscience. Songbirds serve as powerful animal models for this endeavor because they learn their vocalizations (“songs”) in a manner that resembles how humans learn to speak and because vocal learning in songbirds is regulated by discrete brain circuits […]

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Stability of Protein-PEDOT:PSS Coating for Implantable Electrodes

Medical devices that are implanted into the human body allow for continuous medical monitoring and intervention, such as stimulation, recording, and drug delivery. Cardiac pacemakers and insulin pumps are examples of novel technology implanted for long-term treatment. For the treatment of neurological disorders, recent advances in neuroengineering consider the use of implantable electrodes. However, these […]

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Studies of CNNM-TRPM7 complexes

It has recently been shown that the tumour suppressor CNNM and TRPM7 bind each other and are coordinately regulated. We propose to determine the structure and function of the complex using cryoelectron microscopy and ion transport assays. A PhD student from the Gehring laboratory will spend four months working in the Runnels laboratory designing and […]

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Digital Tools and Techniques to Enable Mass Customization of Prefabricated Housing Year Two

The intended research aims at bringing the design and production process of the industry partner, BONE STRUCTURE into a new level of customization, that involves effective homebuyers participation in the design of their homes, using cutting-edge computatioanl design techniques. The customization process is initiated with a layout design; roomblocks modifications, till selection of appliances and […]

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Development of lead-free solder alloys for electronic assembly Year Two

Recent environmental concerns and legislations over the use of lead are driving the microelectronics industry towards intensive search for lead free solder alloys in electronic packaging. Among many lead free solders, Sn-Cu-Ag system has been regarded as the most promising and attractive candidate alloy system for the conventional Sn-Pb solder alloys, owing to its wettability […]

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Ru-Ni-based catalysts for CO2 capture and methanation

A new collaboration between l’Institut de Recherche sur la Catalyse et l’Environnement de Lyon (IRCELYON) and the Catalytic & Plasma Process Engineering Laboratory (CPPE) at McGill is being established. The project aims to utilize dual functional materials (DMFs) for (1) CO2 capture, and (2) subsequent CO2 hydrogenation to methane (CO2 methanation). We intend to couple […]

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Antibacterial agents derived from chemically modified bacterial cellulose

Cellulose as the most abundant natural polymer is produced is produced by trees, and some microorganisms. Certain types of aerobic bacteria such as Gluconacetobacter xylinus are able to biosynthesize a unique extracellular form of this polysaccharide, known as bacterial cellulose (BC). However, Similar to other nanocelluloses, BC exhibits properties such as insolubility in common solvents […]

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