Mass spectrometry imaging of glucocorticoids in the mouse thymus

The project aims to better understand how stress hormones (i.e., glucocorticoids) are synthesized in the thymus, a key primary lymphoid organ of the immune system. Stress hormones are critical for proper thymic development and immune function. However, many details about how and where in the thymus stress hormones are produced remain unexplored. As part of […]

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FeatTS-Detect : Features-Driven Time Series Anomaly Detection

With the rapid growth of sensors in Cyber-Physical Systems such as clinical data, industrial systems and data centres, there is an increasing need to monitor these devices to secure them against anomalies. This is particularly the case for streaming clinical data. Indeed, the timeliness revelation of anomalies in these data can save the patient’s life. […]

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New directions for old aluminum: Innovating aluminum recycling through novel processes and materials

Demand for aluminum alloys is increasing rapidly, facilitation of electric vehicles being but one example. A consequence is increasing scrap supply; a positive as aluminum is highly recyclable with it consuming a fraction of resources compared to using primary aluminum. There is a growing concern, however, as high-performance alloys are compositionally tuned to maximize performance. […]

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Well-Defined Silica-Supported Titanium Catalysts for Introducing Nitrogen Functional Groups

Nitrogen is a key component in many molecules used as medicines, materials and fertilisers. Adding nitrogen into molecules is currently inefficient and expensive: it requires multiple steps and creates a lot of waste. Alternatively, it is possible to introduce nitrogen by processes called hydroamination and hydroaminoalkylation. These reactions are 100% atom efficient (all of the […]

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Engaging youth in participatory research: A trans-national Canada-France study to improve youth mental health and wellbeing in the context of the COVID-19 pandemic

The COVID-19 pandemic and corresponding health, social and economic implications have resulted in significant life changes for youth. One of the most critical impacts has been on youth mental health and wellbeing. To address the mental health needs of diverse youth populations during and following the COVID-19 pandemic, the proposed internship will advance the CIHR-funded […]

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Smart contracts’ governance: A new order for economic activity?

Recently, a new form of organization—a decentralized autonomous organization (DAO)—has emerged as a novel form of governance. DAO is an organization represented by programmed operating rules that determine who can execute changes to the rules of applications built on blockchains. Through ownership of governance tokens, DAO grants its stakeholders such as users, developers, and contributors […]

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Developing a Sensitive and Quantitative Opioid Detector for Use in a Clinical Setting

The opioid epidemic is a serious health crisis in Canada, North America, and globally and has worsened during the COVID pandemic. Opioid treatment strategies are at the forefront of efforts to tackle this crisis. To improve the replacement therapy currently used, an estimate of tolerance is required. This proposal takes an existing proof-of-concept opioid detection […]

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Fingerprinting favourable volcanic horizons for precious and critical metal deposits in the Golden Triangle, British Columbia

This project will help determine the history and distribution of the volcanic rocks which hose important copper, gold and critical metal deposits in the so-called “Golden Triangle” of NW British Columbia. The interns involved will apply various methods to determine the age, chemical composition and distribution of the Jurassic age volcanic rocks of the Hazelton […]

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Capacity Building for Competitiveness in Aboriginal forestry

This project recognizes the significant business challenges First Nations forestry enterprises face which have the effect of limiting the benefits to First Nations from forests (Wellstead and Stedman 2010). There is limited awareness of the conditions that affect the success and failure of Aboriginal enterprises in the forest sector (Trosper et al 2008). Research on […]

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Characterization of in-feed materials of wood pellet plants

The key objective of this research is to measure the quality of in-feed materials of wood pellet plants around the provinces of British Columbia and Alberta. This research will include the collection of in-feed materials from at least eight plants and a series of experimental measurements in in-feed properties such as moisture content, ash content, […]

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Optimizing medical marijuana: developing genetic and chemical resources to improve the quality and quantity of cannabinoid metabolites in Cannabis sativa L strains

Cannabinoids are synthesized and accumulate in Cannabis plant hairs called glandular trichomes, which are particularly abundant on female flower buds. Cannabinoid content and composition vary dramatically among Cannabis strains, with two general groupings distinguished: marijuana strains, defined by high THC and low CBD levels, and hemp strains containing low THC and high CBD (or low […]

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Assessing the ovarian cancer microenvironment with optical coherence tomography and artificial intelligence

Ovarian cancer is one of the deadliest gynaecological conditions in the developed world, as it is often detected late into progression. Efforts to improve surgical and chemotherapeutic approaches have only made marginal improvements to patient outcomes over the past 30 years, but there remains potential within immunotherapeutic approaches. Understanding the tumor microenvironment, and particularly the […]

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