The goal of this research is to improve breast cancer local control and reduce treatment side effects by demonstrating that a new cold plasma technology, which generates locally specific reactive oxygen species, has an additive positive treatment impact when combined with conventional radiotherapy. This project has the potential to enable a Canadian technology, to become […]

G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs by compounds as varied as photons, lipids, ions, small hormonal or neurotransmitter compounds or larger peptidic and protein molecules. As […]

The molecular mechanisms responsible for the occurrence of metastatic cancer are beginning to be elucidated with the identification of key regulators. Increasing evidence points to tumor cell epithelial to mesenchymal transition (EMT) as an important contributing process to metastatic evolution. The identification of factors that are stimulated during EMT might provide the means to develop […]

Asset allocation – the decision of how to divide a portfolio among the major asset classes such as cash, stocks and bonds – is a key determinant of portfolio performance. Because financial markets go through periods of strong and weak economies, the performance of an asset class varies with shifting economic conditions. These regime shifts […]

Virtual reality (VR) and augmented reality (AR) offer a unique immersive video experience by providing 360-degree video in a panoramic view. Limited bandwidth, demanding high quality, encoder delay, network latency and lack of standards are the main problems to deliver true VR immersive experience. To address these challenges, in this research, we intend to design […]

Heart failure is a complex cardiovascular disease with increasing global burden while the prognosis for patients remains poor. Risk factors and the type of heart failure differ between men and women. These differences can be due to sex – referring to biological differences – or gender – referring to social differences. In our project we […]

Alzheimer’s disease (AD) is a neurodegenerative disorder that is difficult to detect early before apparent manifestations of cognitive decline. Current detection methods rely on expensive and hardly accessible imaging techniques (PET scans). Optina Diagnostics developed a new camera as well as innovative image processing methods to propose a non-invasive test to identify the presence of […]

Les PROTACs sont de nouvelles molécules thérapeutiques ayant pour but de soigner certaines maladies grave comme les cancers. Ces composés sont des molécules linéaires constitués de trois composants principaux : une extrémité permettant de repérer la cible, une autre extrémité permettant de causer la dégradation de cette cible, et enfin un linker reliant les deux. […]

Influenza causes seasonal illness characterized by fever, myalgia and respiratory symptoms which can lead to hospitalization and death. Although it is a vaccine preventable disease, influenza contributes directly and indirectly to a large number of hospitalizations and outpatient visits. More specifically, influenza causes every year approximately 12,000 hospitalizations and 3,500 deaths in Canada, of which […]

Hydro-Québec is a public utility that generates and distributes electricity. Despite selling most of its electricity in Québec, its most lucrative sales are in the neighboring markets. To ensure the best possible quality of service, the transmission system must remain stable, but to maximize profits, the company also wants to increase its transmission capacity to […]

ClosedLoop.ai is an AI-based predictive analytics platform that goes beyond traditional claims-based risk scores to use all patient-related healthcare data to provide both clinicians and care managers with a full breadth of timely, transparent and accurate predictions of health outcomes. ClosedLoop.ai helps value-based providers confidently answer a variety of health-care questions like, which patients are […]

The company Lexum is an undisputed leader in the development of information retrieval tools for the law – statutes, regulations and decisions of courts and tribunals. The project is to improve a new tool offer by the company. The tool is used to retrieve a list of legal subjects from a factual description. With that […]