Composite and foam profiles for building and construction industry: modification of the products and existing extrusion processes

Vision Extrusions Group LTD is a recognized leader in the building products industry. They produce a wide range of products (as shown in Figure 1) including windows, doors, decks, fences, etc. utilizing extruded polymeric profiles as a substitute for wood. In the proposed project, the following objectives have been set by the partner organization to […]

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A wireless headset for power-aware EEG/non-EEG signals processing and seizure warning

Epilepsy is a debilitating neurological disorder affecting approximately 50 million people worldwide (World Health Organization). This project proposes to develop a SMART (Seizure Monitoring At the Right Time) Headset for these patients to monitor their brain signal and track their movements, heart rates and breathing patterns. This headset will have new types of sensors suitable […]

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Scalable Quantum-Enhanced Generative Models for Drug Discovery: Extending QCBM with NQS and CUDA Quantum for Multi-target Inhibitor Design

This project proposes a scalable quantum-enhanced generative model for drug discovery, targeting the design of KRAS inhibitors through the integration of Neural Quantum States (NQS), Quantum Circuit Born Machines (QCBMs), and CUDA Quantum acceleration. By replacing traditional quantum circuits with adaptive NQS representations and extending QCBM capacity to 32 qubits, the framework enables more expressive […]

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Host-pathogen interaction between a three-dimensional tissue model with a binary cell system and dual species biofilm Under Normoglycemic and Diabetic Conditions

Apical periodontitis is a disease caused by the persistence of microorganisms and their virulence factors in the root canal system. This infection leads to inflammation of the soft tissues and changes in the periapical bone structure. Bacteria such as Fusobacterium nucleatum and Parvimonas micra form biofilms that are resistant to conventional cleaning, making treatment more […]

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L2M – Developing Machine Learning Models to Accelerate our In-Vivo Creatinine and Potassium Biosensor Development

Many people with heart failure are not prescribed the full set of guideline-directed medical therapies (GDMT), which can shorten their lifespan and reduce quality of life. One major reason is the difficulty and inconvenience of regularly checking potassium and creatinine levels, which are needed to safely adjust these medications. To address this, we are developing […]

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L2M – Advancing the Commercial Potential of a Novel Simulation Tool for Thoracic Surgery Training

This project will support the commercialization of a new medical training tool designed to help doctors learn how to perform technically complex procedures for cancer staging and diagnosis. The partner organization, University Health Network, has developed a realistic 3D-printed simulation model that enables trainees to safely practice this procedure outside the operating room. Unlike current […]

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L2M_BSI Proposal_L2M Health Validate Helixir

Our academic lab has developed technology that could have potential benefits in the Canadian healthcare system. This technology is highly specialized that combines MRI and interventional cardiac treatment. The intern will determine if our technology can satisfy the needs dictated by various stakeholders in the industry, such that a startup is warranted. This objective will […]

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L2M Validate – Pi16 Therapeutics

The mission of PI16 Therapeutics is to improve skin health for the ~4 million Canadian’s suffering from long-term skin diseases, including clinically dry skin, chronic wounds, and severe burns. PI16 Therapeutics aims to produce skin solutions for these individuals by genetically engineering naturally occurring stem-cell like fibroblasts that express the gene Peptidase Inhibitor 16 (Pi16) […]

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L2M DialySnake: A novel, minimally invasive tool to remove intraluminal fibrin plugs and restore peritoneal dialysis catheter patency

This project will focus on helping to bring the DialySnake, which is a novel medical device, closer to market. The DialySnake is a low-cost, minimally invasive tool designed to unclog blocked peritoneal dialysis (PD) catheters at patients’ bedsides in an average of 5 minutes. Currently, when peritoneal dialysis catheters become blocked, hospitals often rely on […]

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Enhancement of a Pharmacogenomic Treatment Decision Support Tool for Schizophrenia

The GeneSight (GS) Psychotropic Test (AssureRx Health, Inc.) measures individual variations in drug-related genes and recommends optimal drug choices for individual patients. A clinical study will be conducted to validate novel gene markers of antipsychotic-induced weight gain for use in an enhanced version of GS. Sarah Groleau will be responsible for genotyping DNA from 600 […]

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Enhancement of a Pharmacogenomic Treatment Decision Support Tool for Schizophrenia – Year two

The GeneSight (GS) Psychotropic Test (AssureRx Health, Inc.) measures individual variations in drug-related genes and recommends optimal drug choices for individual patients. A clinical study will be conducted to validate novel gene markers of antipsychotic-induced weight gain for use in an enhanced version of GS. Sarah Groleau will be responsible for genotyping DNA from 600 […]

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