Improving the durability of superhydrophobic surfaces is of significant interest in the surface engineering community. We have recently developed a novel superhydrophobic coating with a hard nanocrystalline nickel matrix and embedded hydrophobic polytetrafluoroethylene (PTFE) particles. To further improve the mechanical robustness of the non-wetting coating, the soft polymeric PTFE particles were replaced with hard, hydrophobic […]

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

Sensorineural hearing loss involves damage to hair cells, the sensory transducers of the auditory system, and/or the auditory neurons that transmit this information to the brain. Once these cells are lost the body does not naturally regenerate them. Elsewhere it has been shown that cells of one type may be converted into another cell type. […]

The NSERC Strategic Network for Smart Applications on Virtual Infrastructures is a five-year partnership between Canadian industry, universities, researchers, research and education  (R&E) networks, and high performance computing centres to investigate the design of future application platforms that will deliver software applications of greater capability and intelligence. These application platforms will be supported by an […]

The intern will undertake research and development activities related to a novel functional electrical stimulation (FES) device called the MyndMove stimulator. Activities are intended to improve the electrical output of the MyndMove to deliver controlled and painless electrical stimulation to patients for a variety of applications, such as mobility, pain management and treatment of pressure […]

Cancer is a devastating disease defined by genetic changes that result in the activation of proteins that encourage cell growth or prevent cell death. Modern oncology aims to specifically target these tumour-promoting proteins, which has the secondary benefit of leaving normal cells unharmed, unlike chemotherapy. Recently, a number of drugs that specifically block tumour-promoting proteins […]

The purpose of this project is to support the development of wellness-focused interventions, including weight management, mental health and social well-being for children with intellectual and developmental disabilities (IDD). To date, the focus of health promotion interventions have primarily focused on typically developing children and adolescents, rather than those with IDD. The partner organization, Special […]

A new film coating that can respond appropriately to different pH conditions of the stomach and small intestine (GI tract) was successfully prepared by combining pH-responsive nanoparticles with ethylcellulose polymer. However, the performance of the composite membrane has not been optimized for controlling drug release in the GI tract. Therefore, improvements are to be made […]

Febrile syndromes are among the most common causes of global illness accounting for approximately two billion episodes annually. However, most infections are self-limited and only rarely do they progress to critical illness. Our current inability to rapidly identify the small proportion of individuals who will progress to life-threatening infections (LTIs) is a major barrier to […]

Polymer electrolyte membrane (PEM) fuel cells convert hydrogen and oxygen into electrical power through an electrochemical reaction, producing water and heat. These fuel cells have been considered for automotive powertrain applications. In this proposed work, a set of varying PEMFC materials will be investigated to advance the performance of PEM fuel cells. The fuel cells […]

In January 2016, the Centre for Ambulatory Care Education (CACE) at Women’s College Hospital completed the Homecare Curriculum. This online, simulation-based program is designed to help personal support workers, nurses, and rehabilitation professionals provide better care for older adults who wish to stay in their homes. The program presents learners with 3 virtual home environments […]