The overall objective of this project is to scale up and demonstrate the utility of novel bioaugmentation cultures for BTEX compounds, and associated diagnostic tools to properly deploy the technology. The intern will lead the project team to develop gene-based biomarker tools applicable to the bioaugmentation cultures and apply these tools to samples submitted from […]

The WHO defines health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity”. The holistic nature of this definition provides the basis for an all-encompassing evaluation of health, which is the guiding principle behind health impact assessment (HIA). An emerging area of public concern in […]

Recent discoveries show that neutrophils mainly die by formation of neutrophil extracellular traps (NETs) in Cystic Fibrosis airways. Therefore determining mechanism and identifying FDA-approved drugs that inhibit NETosis could provide novel options to treat CF lung disease. We aimed to do the comparative gene expression analysis during NETosis induced by different NET inducing agents (PMA,LPS,A23187) […]

The NSERC Strategic Network for Smart Applications on Virtual Infrastructures is a five-year partnership between Canadian industry, universities, researchers, research and education (R&E) networks, and high performance computing centres to investigate the design of future application platforms that will deliver software applications of greater capability and intelligence. These application platforms will be supported by an […]

Depression is a disabling condition affecting millions of people. Some of the symptoms of depression make it impossible for people to function in their daily lives. People experience significant levels of memory, thinking, planning and other cognitive symptoms that impair their abilities to go to work, school and take care of themselves and family. What […]

Periodontitis is a polymicrobial infectious and inflammatory disease that can lead to destruction of supporting structures of teeth. Although pathogenesis of periodontitis includes genetic and environmental factors, oral microbial biofilm elicits an inflammatory host reaction. Improvement in patients with periodontitis relies mainly on elimination or at least control of periodontal pathogens. The aim of this […]

Glioblastoma (GBM) is the most common primary adult brain tumor, characterized by extensive cellular and genetic heterogeneity. Even with surgery, standard chemotherapy, and radiation, tumor recurrence and patient relapse are inevitable with a median survival rate of

A recently developed technology called CRISPR/Cas9 allows scientists to quickly and precisely edit DNA in living cells and is about to revolutionize molecular biology and genetics. The success of CRISPR/Cas9 is based on its ease of use, effectiveness and cost efficiency. Our aim is to explore a variant of this technology, CRISPR/Cpf1, for its application […]

Patients who suffer from severe burns require immediate wound closure to ensure survival and facilitate healing. The current gold standard in surgical practice is the use of split-surface autographs, allographs, or skin substitutes, but limitation range from the lack of layered tissue organization, the potential for immunological rejection, and the need for high quantities of […]

During the duration of the proposed project, the intern will become a member of the partner organization’s “Big Data” team, participating in all team activities, and completing research-oriented work for the team. The intern will complete research that will explore and improve upon previous methods of intelligently communicating with customers through personalized emails. This may […]

Firms meet legally established accounting rules by including notes in financial statements that essentially hide key information in plain sight. That is, they contain information necessary to understand the statements, but due to the volume of notes and arcane language may be uninterpretable by even lawyers. However, these notes may be interpretable by a software […]

Search and recommendations drive the majority of sales at KOBO. It is therefore critical to continually improve and tune these algorithms. Our project will explore several questions dealing with integrating information provided by users in order to optimize search and recommendation algorithms: how to integrate user-generated tags in order to enhance search (rather than simply […]