Encoding Bi-specific T cell Engagers into oncolytic vaccinia virus

Through engineering and selection strategies, we have created novel cancer-killing oncolytic viruses (OVs) that are selective for tumours but are unable to grow in normal tissues. A critical component of the therapeutic activity of this class of therapeutics is the induction of an anti-tumour immune response, which can be suppressed in many tumours. One strategy […]

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DARSA (Deep-learning Assisted Radiological Software Application):Innovative Machine Learning approaches for Detecting Pathology inImages

Many aspects of healthcare are time consuming and error prone. Recently there has been great progress in using artificial intelligence to solve a number of problems. One of the best examples of this is image labelling using a type of neural network approach called deep learning. Recent research has shown that deep learning approaches can […]

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IoT-based Rental Item Location Tracking System

The purpose of this project is to add a feature to Rentrax so that business owners can track the physical location of their rental items. Device should be small enough to be hidden in rental items such as bikes. Battery usage of device should be as low as possible so that it doesn’t need frequent […]

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Good Decisions, Diverse Voices: Developing Tools for Equitable Decision Making

Despite the importance of diverse voices in community decision-making, we still do not fully understand how to support sound decision making in a way that is equitable and works to advance agendas of historically marginalized groups. We will draw on notions of equitable representation and urban planning to define equitable decision making, identify value elicitation […]

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Placentia Bay Atlantic Salmon Aquaculture Project

The Fisheries and Marine Institute of Memorial University is partnering with Grieg Seafood Newfoundland to provide 9 internships to students from the Advanced Diploma in Sustainable Aquaculture graduating class of 2021. The proposed project seeks to provide HQPs to assist Grieg in optimizing the novel equipment and systems that will be installed in their land-based […]

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Explore Remote Virtual Technologies Using Real-time Very Long Baseline Interferometry (VLBI)

This program will cement Canada’s leadership in global Very Long Baseline Interferometry (VLBI), a key technology in radio astronomy and geodesy. In partnership with Thoth Technology Inc., our team of leading radio astronomers will (i) develop new capabilities to compress, transport, and process large amounts of data between geographically distinct locations to enable real-time VLBI, […]

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Effect of off-bottom oyster aquaculture on coastal bird populations

The coastal ecosystem of Prince Edward Island (PEI) represents an interface between the open marine waters of the Gulf of St. Lawrence and the sandstone, densely populated province of PEI. It is one of the wildest landscapes remaining in PEI and hosts several species at risk (including the endangered piping plover and red knot). This […]

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Integration of Electromagnetics in Potash Mining Geohazard Analysis

Potash is a mineral that is mined for use as fertilizer in agriculture. Potash accounted for $6.4 billion in exports from Saskatchewan in 2018 and potash mining represents a large fraction of the economy of Saskatchewan. When mining potash, it is important to avoid mining into areas near water-filled porous rocks since this can cause […]

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Electroplated Phosphonate Quaternary Ammonium Antimicrobials for Corrosion, Wear and Antimicrobial Resistant Metal Surfaces

We are proposing to use a rapid, safe and green electroplating process to adhere antimicrobial phosphonate quaternary ammonium materials onto receptive metal surfaces. Pathogenic infections are responsible for approximately 60% of all hospital acquired infections. In order to help stop the spread, high contact surfaces such as bed rails in hospitals, door knobs etc. require […]

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Comprehensive Waste Management Plan and Assessment

Durham Region is committed to responding to the climate emergency by embedding climate change considerations across all elements of Regional business. This research will involve an examination of the Region’s entire waste management system and develop a full life cycle analysis model for GHG emissions which can be used to identify opportunities and support strategies […]

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Evaluation of CO2 Sequestration Opportunities in Lloydminster Post-chops Heavy Oil Reservoirs and Underlying Aquifers

Carbon capture and storage is a feasible, reliable and economic approach to reduce CO2 emission. Llydiminster area on the boarder of the provinces of Saskatchewan and Alberta is an area with significant heavy oil production and a large amount of CO2 resources from thermal operated heavy oil production facilities and oil upgraders. Deploying CCU technology […]

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