Automated Scanning Probe Fabrication for Atomic Scale Devices

With our increasing dependence on technology, the total energy consumption from electronic devices for computation is projected to surpass all other contributions. By creating atomic-scale devices at the fundamental limits in size and energy cost, we can reduce their overall energy consumption while increasing computational power. While proof of concept devices are already routinely created, […]

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How are rapid environmental changes influencing Canadian-origin Yukon River Chinook declines?

Yukon River Chinook salmon have experienced devastating declines in recent years, leading to significant impacts on Yukon First Nation citizens. To address this growing conservation issue, we have collaborated with Yukon First Nations to understand their desires for improving salmon conservation capacity, and how we can support them in this endeavour. Together, we have identified […]

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Investigating WD repeat protein function in the nucleolar biology and cancer

Ribosome biosynthesis is one of the most multifaceted and energy-demanding processes in biology. It involves over 250 factors that transiently associate with the nascent pre-ribosome in a well-orchestrated manner. Importantly, increased ribosome biogenesis has a critical role in cancer initiation and progression. Owing to the advances in cryo-electron microscopy, this pathway’s detailed mechanism started to […]

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Metamaterials toolbox:Tuning heat flow at will in the Si-based materials at nano- and mesoscales

Heat management in semiconducting nanomaterials requires the design of engineered artificial structures, known as metamaterials, where thermal properties can be tuned almost at will by microstructural modifications. Testing a broad range of nanostructures for the particular device applications, with predictive behavior, is a grand challenge especially because of the difficulties associated with the experimental synthesis […]

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Antiviral Treatments for the Development of Enhanced PPE, HVAC Filtration Technologies, and Prevention of Pathogen Transfer on High-Touch Surfaces

The COVID-19 pandemic has illustrated the need for the development and commercialization of enhanced personal protective products, air filtration systems, and high-touch surface coatings which supplant residual disinfection and render viruses inert. The pandemic has also highlighted the need for local supply-chain establishment, including antiviral coating manufacturing and materials sourcing in Canada. This proposal is […]

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Towards improved fittings, better outcomes and increased cognitive capacity with bone conduction devices

It is well known that ‘better’ hearing aid fittings lead to ‘better’ outcomes. In recent years, ‘better’ hearing aid fittings, particularly in the bone conduction space, have benefitted from advancements in verification tools, for example the skull simulator and surface microphone. In turn, these verification tools have aided in the development of individualized prescription algorithms, […]

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Synthesis and characterization of a new generation of bone targeting anabolic prodrugs – Year two

Prostaglandin E2 stimulates bone formation in vivo and exerts its effects through the EP4 receptor. Unfortunately prostaglandin E2 and agonists for the EP4 receptor also cause unacceptable systemic side effects which have limited their clinical use as anabolic agents. We developed novel bone-targeting prodrugs that can deliver EP4 agonists selectively to bone and liberate active […]

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Atmospheric stirred tank leaching of chalcopyrite concentrate in ferric sulfate media catalysed by iodine with air/oxygen injection

Leaching of primary copper sulfide (chalcopyrite) using ferric as the oxidant at ambient temperature and pressure exhibits slow kinetics and poor leaching efficiency. In collaboration with LeadFX, this project aims at developing an atmospheric tank leaching process for copper extraction from chalcopyrite concentrate with iodine as the catalyst. The temperature used will be higher than […]

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IN_SITU: A research study to evaluate & address the digital challenge of Co-Creation between the Arts and Artificial Intelligence

IN_SITU is a research study that investigates the possibilities and challenges of connection and bridge-building between Canadian arts sectors and the most advanced academic research centres dealing with Artificial Intelligence in Canada and beyond. The study will explore how artists and artistic organizations can augment their digital strategies, literacy and intelligence when artists co-create with […]

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Microchannel Plate & Shell Heat Exchanger for Flue Gas Heat Recovery

Natural gas power generation is a cost-effective method of generating electricity. NG power generators have been successfully installed in a wide variety of energy intensive facilities in Canada, including district energy systems, wastewater treatment facilities, schools, nursing homes, hospitals, office buildings, and residential buildings. However, more than 60% of the energy is wasted in the […]

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