Development and validation of BRET-based biosensors for drug candidate profiling

G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs by compounds as varied as photons, lipids, ions, small hormonal or neurotransmitter compounds or larger peptidic and protein molecules. As […]

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Investigating Existing and New Models of Distribution in Canadian Art Book Publishing

In early 2018, the UK-based publisher Black Dog declared bankruptcy. This headline wouldn’t have made a splash if not for numerous co-publishing partnerships held with Canadian art institutions. Black Dog’s liquidation left galleries and museums across the country with books stalled mid-production, resulting in delayed or cancelled exhibitions. Firstly, why were Canadian institutions partnering with […]

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A weighted graph approach to IP geolocation

When you load a page on the internet, or watch a video, or send an email, packets of information travel along a path from your computer to the destination. Where does this path go? If both you and your destination are located in the same country, does the path respect international boundaries? We propose a […]

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Use of XR to address coordination challenges in construction projects

Building design is a complex and iterative process that requires collaboration between designers from numerous disciplines. Quality of design has a direct impact on the project success and poor-quality designs are the leading cause of project delays, reworks, and cost overruns. This research aims to improve the quality of design by focussing on two themes: […]

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Intelligent Vision Based Navigation Systems

Utilizing geomatics sensors such as laser scanners, GNSS, Inertial Navigation Systems (INS), and photogrammetry cameras to provide mobile mapping solutions has been studied and utilized extensively in the past three decades. The data fusion between high-end mobile mapping systems such as laser scanning and imagery-based systems, and low-cost camera systems are still a fertile field […]

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Overcoming Barriers to Sustainable Purchasing: A Case Study of Avocado Co-op

In order to meet global climate change goals, it is necessary for consumers to shift their preferences for products towards more sustainable and eco-friendly options. Two common barriers that consumers experience when purchasing green products are: 1) perceived difficulty of buying green, and 2) skepticism about the quality of green brands. Avocado Co-op is attempting […]

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RLCapture: A deep reinforcement learning based control strategy forswitching between motion capture inspired controllers.

Making robots walk and balance as well as humans is extremely difficult. New techniques involving machine learning have shown promise in getting robots to mimic the movements of humans recorded using motion capture technology widely used for videogames and movies. While these techniques show promise, they are still in development, and have difficulty switching between […]

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Comprehensive study of VCSEL-MMF coupling techniques

Vertical cavity surface emitting lasers (VCSELs) are in high demand in short-reach optical interconnects. Reflex Photonics is a leading company in developing VCSEL-based optical transceivers for the harsh environments. So far, the speeds up to 12.5 Gb/s for a reach of 100 m have been achieved. One of the key bottleneck in developing rugged transceivers […]

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Vela Canada; Building Social Capital

Research has shown that persons with disabilities have difficulty establishing relationships and becoming involved in their communities, which can generate barriers to generating and maintaining social capital. Microboards are small groups of people who have agreed to collaborate with an individual with a disability to form a person-centered ‘board’. Microboards have generated anecdotal attention for […]

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