Identifying novel biomarkers and immune response profile correlating to clinical outcome in ovarian cancer patients treated with a T cell activating immune therapy

Cancer afflicts 1 in 8 people worldwide. Recent advancements in bench-to-bedside translational research has resulted in numerous effective treatments. However, a harsh reality still exists in that only ~20% of patients respond positively to treatment. Not all cancers are created equal, which has led to these clinical complexities undermining treatment options. It is our goal […]

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Optimizing Chemical Usage at the Barkerville Gold Mine

The Barkerville Gold Mine will host an intern to conduct a study to optimize chemical usage to extract gold and treat effluents. The gold mine obtains ore from a range of deposits with different mineralogical properties. The intent is to minimize chemical use and therefore reduce effluent treatment requirements thereby reducing overall environmental liabilities and […]

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Discovery of Novel E3 Ligands for PROTAC Development

Protein degradation induced by PROTACs (PROteolysis TArgeting Chimeras) constitutes a novel modality of drug discovery, with advantages over the traditional approach. This approach is still at infancy and there is a lot to learn in this field. The trainees will work under academic supervisors at University of Toronto, who are experts in chemical tool development […]

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Automating Configuration and Performance Management of Data Centers

Data centers (DCs) in network softwarization and 5G eras are significantly different from those operated nowadays by public cloud providers. They are massively distributed, closer to end-users, heterogeneous (e.g., multi-access edge, central office as a data center, etc.) and rely on much more complex technologies (e.g., Network Functions Virtualization [NFV] and Software-Defined Networking [SDN]). This […]

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Electro-fermentation of Lignocellulosic Biomass for High Rate Biofuel Production

There has been a noticeable interest across Canada to deploy new approaches to help address our growing energy needs. Second generation bioethanol production from agricultural and forest residues (named as lignocellulosic biomass), can pave the way for achieving this sustainable bio-economy. Regardless the efforts by ethanol producer companies to develop the technologies of generation of […]

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Bio-sourced reagents for the flotation of minerals in the mining industry

Many mineral ores are concentrated by froth flotation, a process that often uses toxic chemicals to selectively alter mineral surface properties. With increasing regulatory restrictions, the industry could face a dead end with no alternative reagents that are sufficiently efficient, low cost or environment friendly. It has been previously shown that peptides could selectively bind […]

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Using wearable sensor-based technologies to detect changes in health status for prevention of adverse health events and to improve overall quality of life

The project goal is to determine the clinical utility of Orpyx LogR technology to detect gait changes and their efficacy to predict and monitor fall risk. Project I will use existing data to determine sensitivity and specificity for prospective classification of fallers and non-fallers for a composite measure drawn from an extensive battery including single […]

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The Essence of Improvisation: Promoting Emotional Fitness in Employees, Products, and Customer Experiences

My proposal directly builds on my Ph.D. work, which has concerned how musical and theatre improvisation can be applied in business and public health settings to promote cognitive and social-cognitive goals. In particular, Lululemon is interested in harnessing the cognitive principles underlying improvisation in order to promote emotional fitness in two complimentary ways––at a human […]

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Collaborative Indigenous Media and Museums: Participatory Multimedia Production for Indigenous Art and Cultural Heritage

The Bill Reid Gallery (BRG) is a Vancouver based public art gallery committed to the display of contemporary cultural heritage of Coastal First Nations. In addition to traditional gallery exhibitions and programing, the BRG also creates an accessible archive for the communities they serve, the city of Vancouver and the general public. This Elevate fellowship […]

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Validation of novel neurofeedback training engine for improving brain health in aging and neurodevelopmental disorders – Year two

Memory impairment is the most common complaint associated with aging. Promising interventions based on research are generally reserved for clinical settings. Technological advancement has now made it possible to administer neurofeedback, an established technique for self-regulating brain waves, using portable technology. xSensa Labs, the partner organization, has developed a digital solution that translates research protocols […]

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