Development and Delivery of Inhibitors for Viral Pathogenic Deubiquitinases

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

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Mental Health: Strategies for Resilience

Mental Health First Aid (MHFA) training is a 12 hour course that was developed in 2001 for health care workers to better support clinical patients in mental health crisis. Evaluations of the training indicate that individuals who take this training improve knowledge of mental health disorders (e.g., psychotic disorders) and are better able to provide […]

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Mapping quantitative trait loci for disease resistance to Infectious salmon anemia in a commercial strain of Atlantic salmon

This research project is intended to take the first steps forward in breeding hardier, disease resistant Atlantic salmon. Infectious salmon anemia is a disease of Atlantic salmon that has led to millions of dollars of losses within the aquaculture industry yearly on a global scale. Through a combination of genomic data and disease trial data, […]

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Light collection optimization with semiconductor photodetectors – Year two

Better light collection by photodetectors would automatically improve signal to noise ratio and photodetector performance. For example, for the positron emission tomography application, it would result in a better image quality for a lower dose. The main cause of the light loss is too much reflection of light that is trying to travel from the […]

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Screening of natural compounds for their anti-glycation activity on collagen fibrils using biochemical and biomechanical assays

Since the beginning of recorded time, humans have been developing ways to make themselves more beautiful or otherwise change their appearance. The hair-care industry itself has a huge global economic power: its estimated total value is $47B annually. However, beauty does not come without a price: methods currently being used for hair colouring and styling […]

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Efficient Signal Processing and Radio Resource Management for High-Throughput and Low-Latency Massive MIMO Cellular Systems – Year two

Future cellular systems must accommodate increasing demand for very high throughput and low latency data services. Massive multiple-input multiple-output (MIMO) approach involving base stations equipped with much larger numbers of antennas than the numbers of users served promises to significantly increase network capacity, while nonorthogonal multi-carrier transmission is expected to dramatically reduce the latency. Integration […]

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Characterizing fucoidan-degrading enzymes from marine bacterium

Fucoidan is a polysaccharide found in brown algae (seaweed). ARC Medical Devices Inc. markets fucoidan purified from brown algae for post-surgical veterinary use to reduce interorgan adhesion development. This product works very effectively, prompting a desire to develop a similar product for use in humans. The challenge to this, however, is that fucoidan is an […]

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Enhancing service quality in community health care through preference-based scheduling

In this project, the intern will develop an integrated patients and care givers scheduling system for the allocation of health care resources in community health care. This system provides patients with an online preference collecting interface for them to express their preferences on time, location, and care givers when estimating their service costs and booking […]

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Mise au point d’un entraînement perceptivo-cognitif couplé à la reconnaissance tactique chez les athlètes

Le but du projet de recherche sera de développer un nouvel entraînement cérébral (perceptivo-cognitif) de pointe pour améliorer la performance des sportifs de haut niveau. Cet outil virtuel multitâche (Figure 1) combinera un exercice de traitement de scènes visuelles dynamiques complexes (NeuroTrackerTM) et un exercice de reconnaissance tactique spécifique (ex : tir ou passe). Les […]

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Creating a platform to collect / publish / analyze / control communication data streams

The NSERC Strategic Network for Smart Applications on Virtual Infrastructures is a five-year partnership between Canadian industry, universities, researchers, research and education  (R&E) networks, and high performance computing centres to investigate the design of future application platforms that will deliver software applications of greater capability and intelligence. These application platforms will be supported by an […]

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Mathematical modelling and numerical simulation for efficient sprinkler system

InteliRain Inc. has developed an effective sprinkler system producing excellent uniformity water distribution for regular or irregular areas but using 30% less water compared to most existing standard industry system. However, the performance of the InteliRain system deteriorates rapidly when it is tested in an open field with wind effect. In this project, the intern […]

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