Assessing the immune response to stem cell-derived beta cells and associated bioprinted devices for diabetes cell therapy

Type 1 diabetes (T1D) is an autoimmune disease where pancreatic beta cells are destroyed and no longer produce insulin, a hormone that maintains healthy blood sugar levels. People with T1D must replace insulin with injections or a pump. Although insulin is lifesaving, maintaining normal blood sugar levels is often a struggle for people with diabetes. […]

Read More
Studying the oxygenation of 3D printed pancreatic tissues

Most people with type 1 diabetes control their blood sugar levels through frequent blood glucose monitoring and insulin injections or infusion. Insulin therapy is life-saving but also life-altering and leads to decreased life expectancy. Instead, insulin-producing cells could be transplanted in devices which would prevent their rejection by the immune system. The design of these […]

Read More
Closed-loop flow control for microfluidic 3D bioprinting

Aspect Biosystems is developing a novel microfluidic 3D bioprinting technology that has the potential to fundamentally change the way many diseases are treated through the creation of functional human tissue. The technology manages highly complex fluid handling operations and requires sophisticated control systems to deliver reliable and repeatable results. This project is focused on developing […]

Read More