Structural modeling for glycosaminoglycan/peptide complexes

Glycosaminoglycans (GAGs) are biological anchors for growth factors (GF) and other chemical substances. The binding of these substances to GAGs can be modified in times of need. For example during wound healing the increased number of GAGs in the injured areas enables a very localized increase in growth factors and chemokines necessary for wound healing. […]

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AI Enabled Subnetwork Selection

Cancers are heterogeneous disease that hijack many of the body’s normal biological processes. Additionally, tens of thousands of genes are involved in each person’s normal biology, while only a fraction of those are repurposed by cancers to drive disease. At an individual level, utilizing entire transcriptomes is rare, as there is too much information for […]

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