Equine Mesenchymal Stromal Cells Ability to Help Fight Bacterial Infections

Antimicrobial resistance is a recognized and growing problem in equine medicine. Mesenchymal stromal cells (MSC) have recently been shown to have antimicrobial properties. We are interested in exploring if equine MSCs can reduce bacterial growth in vitro and to understand the cellular mechanisms governing such an effect. This project will provide a baseline for a […]

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Enhancement of Canine Adipose Tissue-Derived Mesenchymal Stromal Cells Immune-Modulatory Properties and In Vivo Feasibility Testing in Elbow Dysplasia Patients

Osteoarthritis is a major cause of disability in dogs. Today, the therapeutic role of mesenchymal stromal cells (MSCs) as a potential treatment for immune and inflammatory disorders is well-defined. We are interested in exploring the immune-modulatory property of canine MSCs with the aim of exploiting it as a potential therapy in dogs with Elbow Dysplasia. […]

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Follow up of horses treated with stem cells at eQcell Inc.

For over 10 years, eQcell Inc. has been treating horses with stem cells. In order to efficiently direct future research, a full picture of the efficacy of past treatments is necessary. This project will follow up with all clients across 8 clinics to collect an up-to-date snapshot of previously treated horses’ health and progression or […]

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Interrogation of small RNAs in MSC chondrogenic potency

Injuries involving joint cartilage such as osteoarthritis (OA) are some of the most common causes of lameness and pain in equine. Sophisticated means of monitoring joint health status are needed to allow early detection and intervention as well as monitoring the effect of interventions. MicroRNAs (miRNAs), a class of short non-coding RNAs, participate in various […]

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