Currently, the gold standard pharmacological treatment for depression typically take several weeks before becoming effective. This delayed treatment onset can be devastating because of increased rates of suicide during this wait-period. Thus, there is a need for rapid acting antidepressant drug treatments. Strikingly, a single infusion of ketamine can result in alleviation of depressive symptoms […]

The proposed project will explore variations in the whole brain after 1 year of treatment that may exist between those who are taking an injectable antipsychotic versus those who are taking an oral antipsychotic in a cohort of first-episode of psychosis. All patients are treated in a naturalistic, early intervention setting at the Douglas Institute […]