Local in situ Controlled Delivery of Biphosphonates in Bone Metastasis

We propose to develop in collaboration with Medtronic Canada a bioceramic drug delivery system for the local controlled release of Biphosphonates (BP) – drugs that prevent bone resorption – to promote both tumor inhibition and bone regeneration at the site of bone tumor resection, eliminating the need for high systemic doses and side effects associated […]

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Development of Cerebral Perfusion Technology

Medtronic is a global medical device company and leader in patient monitoring technologies that has a key area of interest for developing technology to effectively monitor patients’ cerebral blood flow (i.e., perfusion) in relation to systemic blood pressure. Maintaining a prescribed intra-operative blood pressure range for patients does not guarantee a healthy cerebral blood flow, […]

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Non-contact vital sign detection of the newborn – Year two

Medtronic is a global leader in medical technology and biomedical engineering, working towards non-contact vital signs detection. This technology would be especially helpful in the case of high-risk or premature newborns. Continuous or at least frequent monitoring of newborns outside of clinical environments improves quality of life for parents and newborns recently discharged from the […]

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Development of novel MRI quantitative measures to correlate degenerative changes in the cervical spine with neurological dysfunction

Patients with cervical spine degeneration are difficult to diagnose and treat. Some patients will not benefit from surgical intervention while others require immediate surgical management to avoid permanent neurological deficits. Distinguishing between these patient groups is very difficult, and not effectively done with current protocols. Medical imaging is part of the current diagnostic protocol for […]

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