Investigation of the solubility and tissue distribution of cannabinoids

Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), two main phytocannabinoids from cannabis, have demonstrated biological effects and potential therapeutic uses. However, their functionality when consumed orally could be limited due to poor water solubility and low utilization rate in human body. To make the cannabinoids more soluble, liquid formulations are being developed using food-grade oils and/or phytoglycogen, […]

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Monodisperse PhytoSpherix Nanoparticles Modified for Key Applications in Personal Care, Food and Nutraceuticals – Year two

Our previous work has shown the promise of monodisperse phytoglycogen for many applications. However, these experiments only scratch the surface of potential uses since the chemistry of the particles (as extracted) is fixed. Nanoparticles offer very high surface areas, and glucose units are easily modifiable, thus there exist a multitude of ways to chemically modify […]

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Evaluation of NanoDendrixTM stability; phytoglycogen resilience in simulated oral cavity conditions

NanoDendrix™ is a completely natural form of glycogen, sourced and produced from plants by a patented green process developed in Guelph, Ontario. Recent studies have revealed many valuable properties and performance characteristics of NanoDendrix, such as its antimicrobial effects, which have wide-ranging implications for clinical use. The proposed internship will evaluate NanoDendrix for use in […]

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Towards a sustainable anti-biofilm technology based on natural materials

Biofilms, surface-adherent microbial populations with enhanced tolerance to antibiotics and disinfectants, are widely-known contamination sources in environmental, industrial and medical settings. Novel approaches for the prevention and remediation of biofilms using nontoxic materials are urgently required. Interestingly, natural polysaccharides and nanopowders have anti-biofilm properties. We will develop a sustainable anti-biofilm technology using PhytoSpherix™ (Mirexus), a […]

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