Single-molecule analytics of RNA/DNA drug constructs interacting with RNA targets and with lipid nanoparticle delivery vehicles

In this project, the interns will develop a new set of tools and techniques to provide new scientific insights into the detailed interactions that occur between drug and target molecules in the human body. Understanding of these interactions is critical to design better, more effective, and more precisely targeted drugs. The problem is that current […]

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Nanoscale toolset for formatting and visualizing single molecules: validating applications and miniaturized flow cells

The “CLiC” microscopy technique was invented and developed by Prof. Sabrina Leslie and her lab at McGill. It is ideal for formatting and visualizing single molecules, like DNA and proteins, with advantages that overcome the limitations of other single-molecule techniques. Due to the increasing interest in the technique from academic and industrial researchers, Prof. Leslie […]

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