Implementation of a low barrier hydromorphone distribution program to prevent fatal overdoses

North America is experiencing an unprecedented opioid overdose epidemic driven by the proliferation of fentanyl and fentanyl-adulterated drugs. Based at the BC Centre on Substance Use (BCCSU) and in collaboration with the BC Centre for Disease Control (BCCDC), I will undertake an ethno-epidemiological study to evaluate the implementation, uptake, and effectiveness of a novel low-barrier […]

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Improving Resource Estimation and Reconciliation with Machine Learning

Models quantifying the grade and tonnage of mineral deposits form the basis of important and costly decisions for planning, optimization and extraction of a natural resource. Models are initially generated from sparse exploration sampling; however, information is continuously collected until resource extraction. Predicted values that reconcile well with true values following extraction instill confidence in […]

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Automating Configuration Management and Deployment in Large-scale Data Centers Augmented with Edge Data Centers

Data centers are now growing and expanding massively. They are large scale and heterogeneous. In addition, they rely more and more on emerging technologies such as Software Defined Networking (SDN) and Network Functions Virtualization (NFV) with “network softwarization” as their key feature. Moreover, they are now being augmented with edge data centers rooted in concepts […]

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Developing solutions for safer harvesting techniques on steep terrain

The forest industry in British Columbia (BC) is facing increasingly difficult challenges regarding fibre supply. New winch-assist technology that enables fully mechanized ground-based forest harvesting on steep terrain has been increasingly used in BC since 2016. The new systems have improved safety and provide access to fibre that was previously uneconomic. New low-consumption small-size cable […]

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Effective knowledge translation of evidence-based best practice for healthy lifestyle behaviours – Year two

The research supports the effective knowledge translation of evidence-based best practice information related to healthy lifestyle behaviours. Over a two-year period, the post-doctoral fellow will create a series of knowledge translation tools that can be used in the effective primary and secondary prevention of chronic disease through lifestyle behaviour modification. Our proposed initiative will capitalize […]

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Use of pulp mill residues as construction and geotechnical materials

Heat and electricity generation from biomass combustion in power boilers and co-generation plants produces large quantities of ash residues in British Columbia (BC) each year. In 2013, approximately two thirds of the produced ash were landfilled in Canada and only the remaining one third beneficially utilized. On the other hand, high-quality construction materials are rare […]

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A Novel Combination Therapy to Target Primitive Acute Myeloid Leukemia Cells – Year two

Modern molecular targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute leukemia patients. This is largely due to the survival of some leukemic cells that possess unique properties and can cause treatment failure or relapse, warranting identification of new, distinct targets for improved therapies. In collaboration […]

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Development of new classes of bio-relevant linkers for PROTACs and other conjugates using new technologies – Year two

Les PROTACs sont de nouvelles molécules thérapeutiques ayant pour but de soigner certaines maladies grave comme les cancers. Ces composés sont des molécules linéaires constitués de trois composants principaux : une extrémité permettant de repérer la cible, une autre extrémité permettant de causer la dégradation de cette cible, et enfin un linker reliant les deux. […]

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Towards creating intelligent heat stress monitoring and management solutions to safeguard health and wellness

The scientific challenge for this research project is to advance our understanding of the impacts of heat stress in heat vulnerable workers and to use this information towards the creation of intelligent heat stress monitoring and management solutions to safeguard health and wellness. Currently, our understanding of the effects of heat exposure on vulnerable individuals […]

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Effectiveness of vegetation and habitat characteristics as predictors of insect parasitoid populations

Climate change, land development, invasive species, and other disturbances can alter the composition, structure, and functions of native vegetation across landscapes. These disturbances also impact insect parasitoids, which are a key, and often overlooked, component of biodiversity. By their ability to control other insect populations, they are integral for fostering resilient and functional forests. Understanding […]

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CCREST: Cold Cracking by Resonance Energy for Sustainable Technologies

The project is a demonstration of Advanced Energy Technologies (AET)’s patented refining process for upgrading heavy oil products without diluent or extreme heat treatments. This produces lighter, higher value oil that is easier to work with throughout the process stream, with greater efficiency and less cost. AET will be conducting demonstration runs of the Hydrogen […]

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Service Life Predictions for Machined Components of Nickel-based Superalloys

Nowadays in aerospace industry, the main concern is to reach an optimum, reliable, and reproducible manufacturing process with a high predictability of the components’ service life and the lowest production cost. Machining is one of the main manufacturing processes for industrial parts which can change the surface characteristics of materials. The main aspects of these […]

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