Assessment of the neuroprotective effects of a novel natural product derived formulation for the treatment of Parkinson’s disease

“Parkinson’s disease (PD) is a neurodegenerative disorder that affects approximately 1.5% of the global population over age 65. Current therapeutic interventions for PD are typically limited to attempts to correct the depletion of dopamine once motor symptoms become moderate to severe. Interventions with the potential to improve the cognitive function and quality of life of […]

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Experimental and Mathematical Modeling of Flow Instability in Heavy Oil Recovery Processes

This research project with the industry partner Saskatchewan Research Council focuses on the displacement front instability in heavy oil recovery processes such as water flooding, solvent injection and polymer flooding. In those processes, the less viscous displacing fluid usually moves faster than the more viscous displaced heavy oil. This results in an instability that manifests […]

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Implementing a novel infectious disease diagnosis assay to a microfluidic device

Infectious diseases ranging from avian influenza to Ebola virus infection are among the most serious health emergencies in Canada and globally. Current diagnosis methods such as cell culture, ELISA and PCR suffer from inaccuracy, high-cost and lengthy procedures. Therefore, there has been a growing trend to develop new point-of-care diagnostic tools and microfluidic devices are […]

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Enhancing water stress tolerance in soybean through phytoglobin manipulations

The purpose of the project is to generate soybean plants able to tolerate whole plant submergence and waterlogging (soil submergence). This will be achieved by inducing Pgb, a gene normally present in soybean and known to confer tolerance to excessive humidity, through genetic manipulations. Correlative studies between Pgb expression and performance under excessive water conditions […]

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Optical determination of membrane defects and correlation with fuel cell performance and durability

There is a strong push toward producing fuel cells on a commercial scale. This means a greater focus on production speed and yields with a need to understand the unintended features that arise from larger-scale manufacturing processes. This project requires the set up of state-of-the-art, camera-vision, defect detection equipment to find and collect observed membrane […]

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Thermodynamic Analysis of Liquefied Natural Gas Refueling Stations and Onboard Fuel Storage Tanks for Mobile Applications

Liquefied natural gas (LNG) has up to 20% CO2 and 90% NOx fewer emissions than diesel; making it a cleaner alternative fuel for mobile applications. LNG has high volumetric energy density and is cost effective ($0.5 cheaper than diesel gallon equivalent). However, LNG is stored at low temperatures (-162ºC) and releases boil-off gas that contributes […]

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Development of Ex-situ Mechanical Durability Tools and Thermo-mechanical Design Curves for Fuel Cell Membranes

Hydrogen powered polymer electrolyte membrane fuel cells (PEMFCs) are a clean energy technology that generates electricity without harmful emissions at the point of use. Current R&D efforts mainly target to commercialize PEMFCs through cost reduction and durability enhancement. The lifetime of PEMFC is limited by the degradation and failure of the polymer electrolyte membrane (PEM). […]

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Encapsulation strategies for the enhanced performance of active ingredients in foods and non-food products

“Functional foods and cosmetics contain physiologically active compounds. However, many active ingredients are susceptible to degradation and/or are not efficiently absorbed by the body. It is increasingly recognized that the composition and physical structures of the products, and interactions between ingredients in the matrix can impact the stability and availability of active ingredients. Encapsulation is […]

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High Bandwidth Biometrics Data Hosting and Analytics in Cloud-based Storage Systems

Cloud hosting environments include large scale distributed storage systems. With the advent of Big Data, especially newer biomedical and biometrics data, collected from wearable monitoring devices, there is a high need for Cloud-based solutions for large scale storage and high bandwidth on-the-fly data analysis for such data. A key problem for IT companies that collect […]

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Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic […]

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