During primary immune responses, dendritic cells (DC) are the principal antigen-presenting cells (APCs) that initiate adaptive immune responses. DCs present pathogenic antigens (such as virus, bacterium and tumour) to induce CD4 and CD8 T cell responses via MHC-I and MHC-II pathways respectively. Recently, our lab has discovered that CD74 molecules not only promote MHC-II but […]
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