Hybrid modeling framework for flood prediction

A hybrid computational framework for short-term flood prediction in urban watersheds (characterized by overland runoff) will be developed to improve prediction accuracy. The framework aims to accurately predict an event, e.g. flood or no-flood, as opposed to traditional methods which estimate water flow characteristics, e.g. 6 feet above flood stage. Successful early prediction of these […]

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Treatment

Edson designs and manufactures innovative machines used for case packaging of goods, food, pharmaceuticals, and other products into corrugated boxes. Machine steps include automatic feeding of the boxes, folding, adding the product, and closing the box top. Market pressures require client ability to swiftly change over to package a new product. Edson must also be […]

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CFD Analysis of the Microsys Cold Gas Inflation System

Microsys is a Mississauga company that designs and sells specialized test equipment to airbag manufacturers worldwide. The Cold Gas Inflation System (CGS) allows these manufacturers to test the inflation characteristics of airbag systems in a simple, safe, and inexpensive manner. The CGS involves the rapid discharge of a compressed gas, which the company would like […]

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Optimization of Mont-Wright open pit mine planning and design using an integrated Geostatistical-Geomechanical approach

This research project aims to develop an integrated geostatistical-geomechanical approach to address the spatial distribution of rock mass mechanical properties, for use in optimization of Mont- Wright open pit mine planning and design. This approach allows a better understanding of rock mass conditions based on limited sampling locations. The methodology would allow the inherent heterogeneity […]

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Pharmacodynamic distribution of docetaxel andcabazitaxel in prostate cancer xenografts, and evaluation of pantoprazole to enhance their activity

Chemotherapy drugs target and kill rapidly-dividing cells located closest to blood vessels, but do not penetrate deep into the tumor. Limited drug distribution in tumors is an important cause of drug resistance. A method to increase tumor drug delivery and combat resistance is the subject of this proposal. To counteract chemotherapy resistance, the use of […]

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Structured Assets’ Value-at-Risk: Measurement and Sensitivity Testing

This project aims to measure the credit risk of Sun Life structured assets portfolio. The objective is to evaluate the accuracy of different methods to assess the credit risk of these types of financial instruments and to evaluate their advantages and limitations. Two methods are proposed to assess structured finance assets risk: Loan Equivalent Approach […]

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Covering designs for efficient de-identification of health records

In Canada, research ethics boards vary widely in the way they interpret risk to patients when their personal information is being re-used for research purposes. However, many research ethics boards will permit information to be shared without consent when they believe there is a low risk of re-identification. PARAT is Privacy Analytics’ de-identification software tool. […]

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The Adoption of Electronic Personal Health Records and Ontario Healthcare Practice Environments

The Centre is working with a health industry-funded global start-up company in the Health ICT (Information and Communications Technology) Sector to empirically examine innovationadoption during the implementation of the company's personal health record application into different health systems and practices within Canada. This comprehensive study will enable a detailed examination of the utility and impact […]

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A Model for Measuring Prevalence of Fetal Alcohol Spectrum Disorder in Canada

Fetal Alcohol Spectrum Disorder (FASD) is the leading cause of developmental disabilities in Canada and is an umbrella term describing the range of effects associated with alcohol use during pregnancy. Currently, we do not know exactly how many Canadians are living with FASD, but we estimate 350,000 and that 3,000-4,000 babies with FASD are born […]

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Improving Efficiency of Operations in Paint Shop and Pre-flight Processes at Bombardier Aerospace Company

The principles of lean engineering design are well documented for the automotive industry – where they have served to revolutionize the efficiencies of North American manufacturing operations. Lean engineering has subsequently been transferred into other sectors – where it continues to generate impressive results. The aerospace industry is faced with demands for efficiency of operations, […]

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