Therapeutic efficacy of tryptamine analogues in a PC12 Cell as a model of depression via assessment of neurite outgrowth and enhanced cellular viability

There is a growing body of evidence that certain combinations of bioactives derived from natural source products may have potent effect on neuritogenesis and foster neuronal cell viability. The effect of neuron plasticity suggests there are potential treatments of major neurodegenerative and psychiatric conditions. In this project we are proposing to use a robust in […]

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CDL-Recovery Intern

The Creative Destruction Lab is a seed venture development program for massively scalable science and technology based ventures founded to positively impact the human condition. The CDL has instituted a unique summer program in light of the COVID-19 pandemic that accelerates ventures that address Covid-19 in terms of information-based solutions. CDL-West, based at UBC Sauder […]

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Fall and Head Impact Acceleration Monitoring of Short Track Speed Skaters

Short track speed skating is a fast-paced sport where athletes routinely reach speed above 50 km/h. It is one of the leading Canadian sports for medal count at the Olympic games. Unfortunately, given the fast-paced and pack-style skating, athletes often fall on the ice, which may lead to concussion. There is no clear data on […]

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Beehive strength modelling using multiclass supervised machine learning

A third of the food that we grow depends on honeybee pollination. Nectar’s mission is to help the beekeeping industry ensure honeybee health to secure our food supply. By leveraging sensor data with labelled data on numerous aspects of beehive conditions, this project aims to develop multiclass classification of key phenomena to improve beehive health […]

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Integrated Amino Analyzer

Develop and design a fully automated and simple to operate amino acid analyzer capable of detecting with high degree of sensitivity the broadest range of amino acid metabolites or molecular structures found in living cells and chemical compounds. Analyzing the makeup of these structures is often the core to understanding the cause of human health […]

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Robust Magnetic Resonance Imaging of Short T2 Tissues – Part 2

Magnetic resonance imaging (MRI) is an imagig modality which can visualize the internal structure of the human body and is free of radiation. In this project, we would like to write a multi-functional and robust MRI software package using ultrashort echo time (UTE) technique to realize the imaging of the tissues, such as tendons, ligaments […]

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Mobilizing the beneficial microbiome of Ontario wheat against Fusarium

Scientists have been interested in the effects that microorganisms have on their host plants for over a century, however, recently researchers have been able to better tackle these questions with the advent of new technology. In particular, beneficial microorganisms associated with roots can increase crop resiliency against disease, pests and extreme weather events, making this […]

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Development & manufacture of a scFv antibody therapy for COVID-19

The current project will assemble a library of molecules known as single-chain variable fragment (scFv) antibodies to treat COVID-19. The scFv antibodies will neutralize the SARV-CoV-2 coronavirus that causes COVID-19 by targeting its spike (S) glycoprotein. ScFv antibodies offer numerous advantages compared to other treatment alternatives such as small-molecule drugs and monoclonal antibodies, and are […]

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Development of novel protease inhibitors active against the SARS-CoV-2 coronavirus

Effective anti-viral therapies are required to treat individuals infected by the SARS-Cov-2 virus, the causative agent of COVID-19. So far, only repurposed drugs have been investigated as treatment to fight SARS-Cov-2 infection. The goal of the project is to use our custom yeast-based screening platform in collaboration with the artificial intelligence algorithms of InVivo AI […]

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