Infectious diseases from a variety of pathogens can lead to serious health conditions such as sepsis. To improve the prognosis and decrease the mortality rate of infectious diseases, point-of-care testing (POCT) of blood biomarkers is a critical approach. Testing of biomarkers such as C-reactive protein, IL-6 and procalcitonin could help identify the type of pathogen […]

Bioprocesses are indispensable for the sustainable production of high value chemical compounds from renewable feedstock. In many processes, genetically engineered strains with a modified metabolism are used. Boosting the performance of such a production host can be essential to make a bioprocess profitable. Computational strain design provides methods to identify interventions in the microbial metabolism […]

A new therapy was developed in order to combat cancers by stimulating our immune system to fight agents the cancer cells in the body. The activated immune system is more efficient to fight the cancer cells than the common drugs, but stimulating the immune system is very expensive and labour-intensive with the currently developed protocols. […]

This project aims at evaluating whether recent results in deep learning models, trained to exploit weak labels can serve to extract meaningful lesion localizations from image-level labels, either from individual scans or given a (longitudinal) sequence thereof. To this end, we will scale up existing models that have been shown to work on 2D images […]

Aux Etats-Unis, plus de 15 millions d’unités de sang sont transfusées chaque année à des patients atteints, entre autres, d’anémies ou de certains cancers. Bien que cette technique soit pratiquée depuis longtemps, plusieurs risques y demeurent associés. Le risque le plus important est l’incompatibilité entre le donneur et le receveur, pouvant résulter dans les cas […]

While at the University of Bath, the project that I will be working on focuses on the development of an all-in-one electrochemical Human Immunodeficiency Virus (HIV) management system. The goal of this project is to develop a device that is capable of actively counting Helper T cells in the human body. Since HIV infects and […]

“Smart” clothing that responds to the wearer offers compelling advantages over today’s inert clothing. By integrating living cells into the textiles that make up our clothing, we can endow them with these “smart” properties. This includes a shirt that begins to smell like flowers when soaked in sweat, pants that “self-heal” after an accidental tear, […]

Allergic rhinitis (AR) is in inflammatory disease characterized by nasal symptoms. It affects 20-25% of Canadians and is recognized as the most common allergic disorder worldwide. Patients can experience one of several types of responses to allergen onset hence a key hurdle to developing effective treatment plans is accurate diagnosis. The allergic responses are characterized […]

The impact of seizures on the life of an epilepsy patient is significant. How they start, propagate and terminate remains unknown. Our hypothesis is that seizures develop in the brain when populations of neurons lose their ability to efficiently parse incoming inputs, known as decorrelation. When these neurons are not able to sufficiently decorrelate incoming […]

Laws of physics combined with computational prowess has allowed us to simulate biological processes at a molecular level, which have a wide range of applications which include guiding experimental observations, designing drugs with molecular precision, and improving bio-sensor technology. However, the existing models use approximations that that limit scope of their applicability, due to the […]

It is hard to understate the critical role access to a patient’s comprehensive medical history plays in diagnosing (and treating) patient illness. For a doctor, knowing the latest prescribed drugs of his patient might, for example, point directly to the cause of an illness — which might be just a drug side effect. Yet patients […]

It is hard to understate the critical role access to a patient’s comprehensive medical history plays in diagnosing (and treating) patient illness. For a doctor, knowing the latest prescribed drugs of his patient might, for example, point directly to the cause of an illness — which might be just a drug side effect. Yet patients […]