DoseBiome has developed a new probiotic that targets several aspects of oral health: dental caries, periodontal diseases, and halitosis. This project aims to understand the exact mechanism of our probiotic’s inhibitory properties against the pathogens associated with the above diseases. DoseBiome is a new start-up in the probiotic/microbiome health sector, and this project will allow […]

Influenza is a viral pathogen responsible for annually claiming thousands of lives (~650 000 per year) and posing a significant threat to all human life. In Canada, Influenza pandemics lead to direct economic losses including medical costs (estimated mean cost per treatment: $14,612.00), and indirect losses such as substantial workplace absence (Avg 10.8 days). Additionally, […]

The objective of this research is to investigate long-term interaction between host cell and pathogen. Research will be proceed using ATPS(Aqueous two phase system) and hydrogel. ATPS enable pathogen to form localized biofilm on mammalian cell tissue. To see long-term interaction, biofilm will be stably localized on mammalian cell using hydrogel, which protect mammalian cell […]

Les granulocytes sont une première ligne de défense très efficace contre les infections. Lorsqu’ils sont en nombre insuffisant ou qu’ils se dérèglent, de graves infections peuvent survenir. La transfusion de granulocytes est alors toute indiquée pour les patients aux prises avec une infection sévère résistante aux traitements habituels. Toutefois, nous ne savons pas si ces […]

The research projects aims to develop the fast photocrosslinking bioinks for visible light-based stereolithography 3D bioprinting. In order to prepare bioinks for 3D bioprinting, alginate was modified with tyramine which is phenol group and gelatin was modified with glycidyl methacrylate. Compound with alginate-tyramine derivatives(Alg/Tyr) and gelatin-methacrylate(GelMA) will improve its 3D printability, mechanical properties and cell […]

Canada is one of the largest canola producing countries. The industry contributes about $20 billion revenue to the Canadian economy. Currently, canola farmers rely on the weather forecast (temperature, moisture, etc.) to decide whether to apply a fungicide. As the Internet-of-Things and sensor technologies get more advanced, farmers are deserved to have better technologies for […]

Sanofi-Pasteur is developing new vaccine formulations that need to be evaluated on their efficacy and potency. Traditionally, the use of animal models to predict human immunity has been accepted as the best way to select vaccine formulations. However, animal models can be costly and time-prohibitive, and the assays employed to assess vaccine efficacy and potency […]

Prosthetic limbs can provide a tremendous improvement in the quality of life and mobility of amputees. The conventional method of attaching a prosthetic limb is a socket that is custom designed to fit to the residual limb. Difficulties with socket fit attachments has led to the use of titanium implants as an alternative method for […]

Artificial Intelligence is powered by data. In general, the predictive power of AI improves with higher data abundance and higher data quality. However, real-world datasets vary greatly in quality and quantity. In drug design, like many other tasks, there is an abundance of low quality data and scarcity of high quality data. This project will […]

MicroRNAs (miRNA) can be used as biomarkers for different types of cancer diagnostics. Therefore, obtaining point-of-care (POC) device for miRNA detection is of high value. Conventional miRNA sensing strategy usually involves reverse transcription PCR or target recycling strategy and hence those techniques are not suitable for POC devices. In the proposed work, electrochemical sensing strategy […]

The concept of artificial cells, or protocells, serves to provide researchers with deeper insights into primitive cellular functions and behaviours through the study of non-living cellular analogues. Protocells are synthetic, cell-like microcompartments designed to mimic key aspects of living cells. Recently, Dr. Pierangelo Gobbo made a remarkable step forward in this research field and utilized […]

Dance is used with increasing frequency as a health intervention and in research designs; despite this increased use, the techniques and mechanisms involved remain poorly understood. Through the use of novel neuroimaging methods that allow for recording of data while subjects are freely moving through space, I aim to elaborate a neurobiological model of dance […]