Non-invasive imaging of hemodynamics is known to enhance screening and monitoring of cardiovascular diseases (a leading cause of death in Canada’s aging population), however clinicians lack an imaging tool that can visualize the complex 3D and dynamic nature of hemodynamics in real-time. To meet such clinical needs, this project will aim to devise the first […]

Il a été démontré que les tumeurs exploitent certains mécanismes liés aux récepteurs immunitaires (point de contrôle) pour échapper à la réponse immunitaire. La mise sur le marché d’anticorps monoclonaux (mAbs) approuvés par la FDA, pembrolizumab et nivolumab en tant qu’inhibiteurs du récepteur immunitaire programmed death-1 (PD-1), et du durvalumab et de l’avelumab qui ciblent […]

The “CLiC” microscopy technique was invented and developed by Prof. Sabrina Leslie and her lab at McGill. It is ideal for formatting and visualizing single molecules, like DNA and proteins, with advantages that overcome the limitations of other single-molecule techniques. Due to the increasing interest in the technique from academic and industrial researchers, Prof. Leslie […]

NanoDendrix™ is a completely natural form of glycogen, sourced and produced from plants by a patented green process developed in Guelph, Ontario. Recent studies have revealed many valuable properties and performance characteristics of NanoDendrix, such as its antimicrobial effects, which have wide-ranging implications for clinical use. The proposed internship will evaluate NanoDendrix for use in […]

Mind reading emotional states of the participants will be done using FMRI machines and self report. The participants will be exposed to various stimuli to trigger an emotional response. These emotional responses will be examined using FMRI machines as well as the self report in order to help classify and locate area’s of the brain […]

In this project, we propose integrating well-known neuroimaging algorithms to model axonal integrity of the white matter over the course of a full season, in collegiate football players. Using these findings as a basis for further investigation, we intend to develop a novel imaging processing tool that will integrate information from different neuroimaging methods to […]

The challenges faced by mammals in adapting to their environment must be tightly controlled in order to ensure optimal body function. Hormones can travel in the bloodstream to reach various parts of the body and execute their biological actions on various organs. However, to reach their target the hormones must leave the bloodstream. That means […]

There has been a noticeable interest across Canada to deploy new approaches to help address our growing energy needs. Second generation bioethanol production from agricultural and forest residues (named as lignocellulosic biomass), can pave the way for achieving this sustainable bio-economy. Regardless the efforts by ethanol producer companies to develop the technologies of generation of […]

Enzymes are macromolecules that speed up the rate of chemical reactions by many orders of magnitude. Different classes of enzymes are present in a cell at different copy numbers to control and fine-tune its metabolism. The kinetics of enzymes differs depending on the physical properties of the local surroundings. Due to the high complexity of […]

Due to increasing rates of childhood obesity, it is important to investigate the relationship between motor skill development, physical activity, body composition and sleep patterns. Previous research in this area has focused on school-aged children and adults, when daily habits have already formed and are difficult to modify. The purpose of this project is to […]

Mesenchymal stromal cells (MSC) hold promise as cell-therapy candidates for numerous diseases such as Graft v. Host disease due to their ability to influence the immune system. MSCs have been shown to be capable of a broad range of immunomodulatory effects, including the production of factors that allow them to serve as Medicinal Signaling Cells […]

Recent scientific breakthroughs have led to the development of methods to differentiate human PSCs (hPSCs) into skeletal muscle cells. This has allowed, for the first time, the development of cellular models to study muscle diseases such as Duchenne Muscular Dystrophy and the possibility to utilize these cells for cell therapy applications. However, the reliability, efficiency […]