Development of fast photocrosslinking bioinks for visible light-based stereolithography 3D bioprinting

The research projects aims to develop the fast photocrosslinking bioinks for visible light-based stereolithography 3D bioprinting. In order to prepare bioinks for 3D bioprinting, alginate was modified with tyramine which is phenol group and gelatin was modified with glycidyl methacrylate. Compound with alginate-tyramine derivatives(Alg/Tyr) and gelatin-methacrylate(GelMA) will improve its 3D printability, mechanical properties and cell […]

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Design of a real-time on-site biosensor system to monitor harmful pathogens and protect canola production

Canada is one of the largest canola producing countries. The industry contributes about $20 billion revenue to the Canadian economy. Currently, canola farmers rely on the weather forecast (temperature, moisture, etc.) to decide whether to apply a fungicide. As the Internet-of-Things and sensor technologies get more advanced, farmers are deserved to have better technologies for […]

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An in vitro Platform of Antigen-Presenting Cells to Evaluate Critical Quality Attributes in Vaccine Formulations

Sanofi-Pasteur is developing new vaccine formulations that need to be evaluated on their efficacy and potency. Traditionally, the use of animal models to predict human immunity has been accepted as the best way to select vaccine formulations. However, animal models can be costly and time-prohibitive, and the assays employed to assess vaccine efficacy and potency […]

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Electrochemical detection of Micro-RNA

MicroRNAs (miRNA) can be used as biomarkers for different types of cancer diagnostics. Therefore, obtaining point-of-care (POC) device for miRNA detection is of high value. Conventional miRNA sensing strategy usually involves reverse transcription PCR or target recycling strategy and hence those techniques are not suitable for POC devices. In the proposed work, electrochemical sensing strategy […]

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Self-Assembly of Nanoparticle-based Colloidosomes via Click Chemistry for the Formation of Inorganic Prototissues

The concept of artificial cells, or protocells, serves to provide researchers with deeper insights into primitive cellular functions and behaviours through the study of non-living cellular analogues. Protocells are synthetic, cell-like microcompartments designed to mimic key aspects of living cells. Recently, Dr. Pierangelo Gobbo made a remarkable step forward in this research field and utilized […]

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An embedded neurobiological theory of dance, why it matters, and how it heals

Dance is used with increasing frequency as a health intervention and in research designs; despite this increased use, the techniques and mechanisms involved remain poorly understood. Through the use of novel neuroimaging methods that allow for recording of data while subjects are freely moving through space, I aim to elaborate a neurobiological model of dance […]

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Entre neurosciences et droit. Le cerveau adolescent moyen du laboratoire au tribunal

Le présent projet s’intéresse aux manières dont les savoirs neuroscientifiques sur le développement du cerveau moyen adolescent circulent des laboratoires de recherche aux tribunaux. Au cours des derniers mois, j’ai réalisé une série d’entretiens aux États-Unis auprès d’acteurs impliqués dans la construction et la diffusion de ces savoirs. Je souhaite à présent me rendre en […]

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Development of biological models for Near Infrared measurements

Spinal cord injuries and other pathologies of the spinal column represent a large cause of disabilities or deaths and significantly affect the quality of life of the individuals affected. To reduce the risk of further injury during spinal surgery and to support diagnostic and treatment, there is a need for a non-invasive real time monitoring […]

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Stage de recherche, culture cellulaire pour la confection d’échafaudages dentaires

Dans le cadre du régime coopératif de l’Université de Sherbrooke, les étudiants au baccalauréat en génie biotechnologique doivent faire 5 stages. Celui-ci serait en fait le 4 ème du cursus de l’étudiante. Ce stage est offert au centre de recherche CSPBAT, qui est en partenariat avec l’Université de Paris 13 avec, comme superviseure de stage, […]

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Investigating Gangliosides in Breast Cancer Subtypes by Imaging Mass Spectrometry

Breast cancer is the most common cancer amongst women. Early detection through mammography and new breakthroughs in therapy have significantly improved the survival rate. Nonetheless, in Canada, approximately one in eight women diagnosed will not live past five years. The study of gangliosides is one avenue to improve prognosis. Found on the cellular membrane, gangliosides […]

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