Evaluating the potential cardiovascular benefits of using the openPAW in persons with spinal cord injury.

In the spinal cord injured population, inactivity is wide-spread, and most causes of death in those with spinal cord injury can be improved by increasing physical activity.  Current electric wheel-chairs exacerbate inactivity in this population by performing all the work required for transportation. The new openPAW device uses bio and environmental feedback (ie. current arm […]

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Statistical analysis of RNA electropherograms to understand the degree and nature of RNA disruption induced by anti-cancer drugs

In this project a molecular diagnostic test, named RNA Disruption Assay (RDA) will be developed. RDA measures an individual patient’s tumor response to chemotherapy and accurately predicts whether the drug regimen will lead to the elimination of the disease after the completion of the treatment. RDA is a measure of RNA structural integrity and is […]

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In vivo and in silico evaluation of multiorgan variability for the detection of critical physiological changes of patients in Intensive Care Units

  The project focuses on the characterization of the evolution with time of the properties of physiological signals recorded in different clinical settings, describing sepsis shock and other clinical complications that are common features in Intensive Care Units. Changes in heart rate, respiratory rate, blood pressure and oxygen saturation will be studied through an array […]

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Project #2 – Optimization of Novel Coatings for Orthopedic Implants

This project seeks to improve the performance of polymer-based spinal implants through the development of a multi-layered coating technology to overcome identified problems. The coating must allow for: a) strong adhesion to the underlying polymer to ensure structural stability; b) radio-opaque properties to allow visualization of the implant during x-ray procedures; c) a bone bonding […]

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Computed Tomography Images Enhancement and Denoising

In Computed Tomography (CT), X-ray radiation is used to penetrate through the internal structure of the patient body in order to produce digital images. Therefore patient could be exposed to certain level of X-ray radiation dose. Accumulation of these exposures beyond certain threshold could increase risk of fatal cancer. Thus it is of paramount importance […]

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A semi-automatic computer aided system for spine diagnosis

This project aims at developing a computerized system for spine diagnosis. This system will improve the efficiency and efficacy of radiologists to diagnose patients’ spine problems. The development of the system involves devising a set of tailor-made mathematical formulation. These formulation are grounded on the state-of-the-art computer vision algorithms and they are capable of capturing […]

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Fluorescently-labeled nanoparticle target for imaging

  There is currently a great need to develop better imaging probes for studying biological process. In this proposed internship, Drs. Pacheco and Hashir will be evaluated an aluminum coated alloyed quantum dot system. These quantum dots are brighter than organic fluorophores and with the aluminum surface coating, these quantum dots are less pervious to environmental factors. This internship […]

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Atlas-based attenuation correction for PET/MRI

Positron Emission Tomography (PET) images need correction for the loss of photons. This loss, or attenuation, is due to interactions with patient tissues. Corrections are currently done with X-ray Computed Tomography (CT), however we are proposing a method whereby Magnetic Resonance Images (MRI) are used. This will be done by creating an attenuation map(?-map). The construction of ?-maps can […]

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Assessing the impact of an electronic patient tracking board on organizational performance

This study will investigate the process of information technology adoption within the Canadian health care system in order to uncover the underlying promoters and barriers to technology implementation. The knowledge gained from this study will assist McKesson and other health IT companies to adjust their technologies and deployment strategies for effective technology implementation. Ultimately, more […]

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Surgical simulator design and evaluation using game engine technology

Surgical training is increasingly being done using simulator technology in order to teach basic skills to residents without risking patients’ lives. However, neurosurgery lags behind other surgical specialties in the adoption of simulators. Since there are no commercial simulators in this domain, the National Research Council has embarked on a neurosurgery simulator development program, in […]

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