Teaching medical students and allied healthcare professionals accurate and patient friendly diagnosis of ear, eye and nasal conditions are challenging tasks due to the lack of realistic models and interaction with patients. The OONTTDP is a collaboration between the Hospital for Sick Children and Otosim to improve the teaching results through development of realistic simulators […]

With the advances of medical imaging, cardiac images have posed great challenges in processing and analysis due to the large amount of data generated. Dynamic Computer Tomography (CT) and Magnetic Resonance Imaging (MRI) images, also referred to as 4D (3D+time) imaging, for example, have great capacity for screening, diagnosis, treatment and prevention of cardiac diseases. […]

This proposal presents research projects to evaluate a new technology, Electrovestibulography (EVestGTM) that holds potential to objectively, quickly and quantitatively measure the severity of concussion, thus aiding in its diagnosis. EVestG signals are recorded painlessly and non-invasively from the external ear in response to a vestibular stimulus; they are the brain signals modulated by the […]

Over the last decade, there has been a growing literature on “brain plasticity” and the role of computer based games for brain health improvement. Most of the focus has been on healthy older adults. While there has been pharmacologic treatment available for dementia for decades, there is no accepted standard treatment for Mild Cognitive Impairment […]

Brain wave technologies allow researchers and clinicians to monitor the brain at work. Our team has developed a new technology that uses electroencephalography (EEG) to provide an online record of different brain functions in a very short period of time. The brain waves recorded by this technology may change normally as time passes and previous […]

Every day, people put their teeth at risk by eating foods that contain a lot of sugar. A lack of brushing teeth causes the build-up of bacteria. The bacteria use the sugars present in these foods to cause the weakening of teeth and if left untreated, can lead to holes and cavities in teeth. The […]

Specific strains of the human papillomavirus (HPV) can develop into cervical cancer. Screening for these types of HPV has been shown as a better early test for cervical cancer. Samples for HPV testing can also be collected by women without going into a clinic. This selftesting method may be a good cervical screening option for […]

Neisseria meningitidis (Nme) is a bacterial pathogen that often colonizes the upper respiratory tract of humans without symptoms, but which may also develop into rapidly-progressing sepsis and meningitis that can be fatal. Nme has evolved elegant means to specifically interact with human cells and proteins in order to colonize, survive and the evade host immune […]

Ventilator assisted individuals (VAIs) living at home are frail and generally cannot perform most daily activities. This is similarly the case for the palliative population of those with amyotrophic lateral sclerosis (ALS). Although these individuals prefer to live and die at home, the family members who care for them often experience stress and poor health. […]

Administration of supplemental oxygen through medical air is a life-supporting measure essential for the management of severe primary respiratory conditions as well as secondary lung injury due to systemic insults such as trauma and sepsis. This medical air is often produced on site through devices which draw, compress and filter outside air in order to […]

Fibroproliferative disorders are the leading cause of morbidity and mortality worldwide. A large group of interstitial lung diseases (ILD) can cause progressive scarring of lung tissues, affecting the ability to breathe. Idiopathic Pulmonary Fibrosis (IPF) is one of the major forms of ILD and is characterized by a progressive decline in lung function. Although the […]

NeuroRx is an imaging contract research organization (CRO) specialized in the central nervous system (CNS) that utilizes state-of-the-art digital image processing techniques to produce accurate and precise outcome measures for clinical trials of drugs in development. Prior to analysis, all scans must pass Quality Control (QC). The goal of this project will be to incorporate […]