TBIFinder : A new approach to identify and properly assess mild Traumatic Brain Injury

Mild Traumatic Brain Injury (mTBI) is a common and devastating condition that severely affects millions of people around the world. Following an mTBI, also known as concussion, a medical professional performs standard neurological tests, however, these tests are very subjective, based on patient-reporting, and provide little to no insight on the severity of an mTBI. […]

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Predicting In-patient Discharges to Identify Bed Availability for Housekeeping During Emergency Department Surge Using Machine Learning Algorithms

Prolonged patient waiting times for an inpatient bed in the Emergency Department (ED) is considered a global crisis and most cited reason for the ED crowding. Inability to move admitted patients from the ED to an inpatient bed due to capacity shortage and inefficiencies in patient-flow affects patient care and patient experiences. Housekeeping is crucial […]

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The effect of a topical analgesic on neuromuscular endurance and pain

It has been shown that topically applied gels, which contain menthol, result in a cooling sensation and reduce the sensation of pain. Because neuromuscular endurance activity leads to sweating and muscle pain we seek to discover the effect of BioFreeze on various forms of neuromuscular endurance activity and muscle soreness. This discovery will require 3 […]

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Strategic BC Salmon Health Initiative: effects of pathogens on the health and conservation of BC’s Pacific Salmon

B.C.’s Pacific salmon are in decline yet the causes are not clear. The role of disease in declining productivity is poorly understood but is potentially an important factor especially given recent controversies involving salmon farms and disease transmission to wild salmon. We have recently collected quantitative data on 47+ viral, bacterial, fungal, and protozoan pathogens […]

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Development of an efficient process to produce influenza virus-like particles in insect cell culture platform

Vaccination is the most effective way to prevent influenza infections. However, the current production of influenza vaccines in embryonated chicken eggs has limited capacity during pandemics or high demand seasons, and is both labor-intensive and time-consuming. Consequently, there is a need to develop a robust production platform that can efficiently accelerate the production process and […]

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Examining the Roles of Mouse Immune Cells in Liver Regeneration

The mammalian liver is known for its regenerative property, capable of fully restoring mass and function after injury. However, when this process is in disarray, chronic liver diseases occur, for which the current solution is liver transplantation. Transplantation remains an imperfect solution as the supply is limited and rejection can happen. Today, 25% of patients […]

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Biological Evaluation of Antimicrobial Materials

Bacterial infections spread from one person to another person by means of a simple “touch” of contaminated surfaces in healthcare units. These infections have become untreatable to most existing antibiotics, thereby accounts for significant mortality rate. Polyamyna Nanotech is developing new antimicrobial coatings that prevent spreading dangerous bacterial infections in hospitals and health care units. […]

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Development and validation of BRET-based biosensors for drug candidate profiling

G protein coupled receptors (GCPRs) are proteins found at the surface of cells are responsible for activating numerous intracellular signaling pathways and thus are involved in regulating about every physiological response. Activation of GPCRs occurs by compounds as varied as photons, lipids, ions, small hormonal or neurotransmitter compounds or larger peptidic and protein molecules. As […]

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Having a pulse for the group: An app-based approach to collecting multiple time-point longitudinal data

The goal of the project is to evaluate and refine an app-based questionnaire that provides a multi-faceted assessment of the social dynamics and culture of teams and organizations. This partnership and multi-phase project with VictoryLab involves (a) systematically examining and refining their questionnaire items to ensure their app-based assessment tool provides valid and reliable insights […]

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Hey Neighbour! Evaluation and Understanding Social Connections and Engagement

The Hey Neighbour! pilot program evaluation intends to draw conclusions about the potential of social policy interventions into urban neighbourhoods. First, we will review the multidisciplinary research trends and approaches related to the question of improving social quality in urban neighbourhoods and communities. This will include review of the terminology, definitions of related terminology, overlapping […]

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ParticipACTION Physical Activity Report Card for Children and Youth and the Global Matrix 3.0: Evaluation and Strategic Harmonization

Global levels of childhood physical activity are declining while sedentary behaviours are rising, leading to the global increase in non-communicable disease. The aim of this project is two-fold: 1. to contribute to childhood physical activity promotion in Canada and worldwide, and 2. to contribute to the international diffusion of the scientific knowledge concerning childhood physical […]

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Understanding the scope for innovations in vaccine technology in the swine industry

Pig production is a vital component of the Canadian agricultural sector. Airborne bacterial pathogens Haemophilus parasuis, Actinobacillus pleuropneumoniae and Actinobacillus suis are major causes of swine respiratory disease and cause rapidly progressing systemic infections that lead to significant morbidity and mortality. We are developing engineered subunit vaccines that can simultaneously target all three pathogens and […]

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