Immunovaccine Inc. is developing cancer vaccines using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation that displays excellent tumor control and provides a long lasting and specific effect. The way by which this vaccine exerts its effect is unclear but the translational team at Immunovaccine is determined to discover its mechanism of action […]

The project involves the modeling of the metabolism of TB. I developed an algorithmic pipeline called MetaMerge, which allowed me to reconcile differences in format, nomenclature, and annotation, between two models of TB metabolism. MONGOOSE, another doctoral project of mine, is a tool for analyzing metabolic network models in exact arithmetic, resulting in consistent, reproducible […]

L’immunothérapie est un traitement prometteur pour soigner le cancer et les infections virales. Ce traitement consiste à éduquer des cellules du système immunitaire, les lymphocytes T, pour qu’ils puissent éliminer les cellules problématiques du patient. Une des grandes difficultés est de fournir de l’aide spécialisée aux lymphocytes T pour faire leur travail. Cette aide vient […]

The last 5 years have seen remarkable advances in speech, image and language recognition tools that have been made available to the public through computer and mobile devices’ applications. Some of these significant improvements were achieved by an artificial intelligence tool known as deep learning (Hinton et al., 2006) that generally refers to a set […]

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

Obesity, type 2 diabetes (T2D) and heart diseases have skyrocketed. Controlling glucose usage and insulin balance can substantially decrease the morbidity and improve the quality of life in affected individuals. Dysfunctional insulin action and energy balance in the body is associated with excessive non-adipose fat storage, particularly in the liver, and elevated circulating lipids, which […]