Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

13270 Completed Projects

1072
AB
2795
BC
430
MB
106
NF
348
SK
4184
ON
2671
QC
43
PE
209
NB
474
NS

Projects by Category

10%
Computer science
9%
Engineering
1%
Engineering - biomedical
4%
Engineering - chemical / biological

The role of hemoglobin-cytarabine in the selective death of acute myeloid leukemia cells

Acute myeloid leukemia (AML) is a blood cancer with very poor prognosis, especially for patients older than 60 years of age. This is in part because of the severe toxicity of medicines available. Less harmful medicines are needed to better treat older patients. Therapure Biopharma Inc. has chemically linked the standard toxic chemotherapy medicine called cytarabine to the blood protein hemoglobin to make a potentially safer and more effective medicine to treat AML. In collaboration with the University Of Waterloo School Of Pharmacy, Therapure Biopharma Inc. will continue to test how well hemoglobin-cytarabine kills AML cells in the laboratory. These experiments will lay the ground work for a future study in patients to test the safety of hemoglobin-cytarabine in patients.

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Faculty Supervisor:

Paul Anthony Spagnuolo

Student:

Alessia Roma

Partner:

Therapure BioPharma Inc.

Discipline:

Pharmacy / Pharmacology

Sector:

Pharmaceuticals

University:

University of Waterloo

Program:

Accelerate

Numerical modeling of interaction between soil and seabed infrastructure during submarine landslides

Large amounts of crude oil and natural gas are located beneath Canada’s ocean floors. Currently, the offshore oil and gas industry makes a significant contribution to the Canadian economy. Although it is not visible as onshore landslides, numerous underwater landslides occur where huge amount of seabed sediment might displace and could result in tsunami in some cases. The failed soil mass might impact seabed infrastructure and could damage or destroy them as reported from some field observation. In the proposed research, the likelihood of submarine slope failure and run-out distance of the failed soil mass will be studied. The consequence of impact loading on offshore pipelines used for hydrocarbon transportation and piles used to support offshore structures or anchor floating facility will be investigated. Five graduate students at Memorial University of Newfoundland will receive training on offshore geotechnical engineering through this research program. The partner organizations (C-CORE & INTECSEA) will receive better tools and design approaches to provide advanced engineering solutions to offshore oil and gas projects.

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Faculty Supervisor:

Bipul Hawlader

Student:

Chike Paschal Okoloekwe, Subhagata Roy, Naveel Islam, Chen Wang

Partner:

INTECSEA

Discipline:

Engineering

Sector:

Oil and gas

University:

Memorial University of Newfoundland

Program:

Accelerate

Development of Sense and Avoid System for Unmanned Aerial Vehicles

Unmanned aerial vehicles (UAVs) have been drawing great attention in the recent decades due to the applications in the pipeline monitoring, film, mapping, agriculture, to name just a few. The question that comes up is: is it safe to share the sky with manned aircraft and other unmanned systems? For the safety of the manned aircraft and UAVs themselves, as well as for people on the ground, the Sense & Avoid system (S&A) should be developed and implemented on the UAVs. This project is to design S&A system with emphasis on the collision avoidance system to improve the safety level of next generation UAVs. The basic idea is to avoid collision with stationary or moving obstacles using the developed system. The project benefits the partner development of the next generation autopilot as it is crucial for the wide range of applications of UAVs and the system has not yet been commercialized.

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Faculty Supervisor:

Inna Sharf

Student:

Bin Yu

Partner:

PrecisionHawk

Discipline:

Sector:

Aerospace and defense

University:

McGill University

Program:

Accelerate

Unseen Enemy: Global Pandemic Knowledge Mobilization

Our deadliest enemies are the ones we cannot see – viruses or bacteria that lurk and mutate, and grow in resistance, until they become an unstoppable pandemic. This year four interns will work alongside the Tech Samurais company to produce key communication tools that will make effective interventions into the Canadian and global conversation about pandemics. Tech Samurais will be providing access to an unparalleled content library, featuring film from the frontlines of the fight against Ebola, polio and measles. Interns will conduct research on information flows and work with Tech Samurais to use this content to build knowledge mobilization tools, a newsgame and a social media strategy that will form the basis of a multimedia site. The project will bring public attention to the global issue of pandemics and will be one of the first in Canada to use innovative new media techniques to change the way we talk about the threat of communicable diseases.

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Faculty Supervisor:

Peter Klein

Student:

Abraham Rami Katz, Alberto Almeida, Sean Wachtel, Mike Lakusiak

Partner:

Tech Samurais

Discipline:

Epidemiology / Public health and policy

Sector:

Information and communications technologies

University:

University of British Columbia

Program:

Accelerate

Minimizing potential induced degradation in crystalline-silicon based photovoltaic solar modules – Year 3

The demand for photovoltaic solar modules has increased tremendously in recent years. Unfortunately, photovoltaic solar modules are prone to potential induced degradation, i.e., a decrease in the power delivered from such modules arising as a consequence of them operating continuously under high applied voltages. This project aims to design a protocol for the accelerated testing of solar modules; we want to speed-up or accelerate the aging of these solar modules in order to identify what materials and configurations in a solar module are less prone to potential induced degradation. We will then use this protocol for accelerated testing in order to systematically identify which materials and configurations are best. Finally, if time permits, the mechanisms of recovery from potential induced degradation are going to be identified, and the device implications of this will be explored. This project will equip our industrial partner, Silfab Ontario, with a strategic advantage over its competitors. This is the third-year of this research partnership.

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Faculty Supervisor:

Stephen O'Leary

Student:

Ravi Sharma

Partner:

Silfab Ontario

Discipline:

Engineering

Sector:

Alternative energy

University:

University of British Columbia

Program:

Accelerate

Development and validation of the OmegaSTAT prototype:A diagnostic kit to rapidly assess omega-3 status

Omega-3 fats are good for our health. When a person has low levels of omega-3s, this can lead to a number of serious health problems, such as heart disease. The typical diet in North America doesn’t have much omega-3 fat, meaning that most people have low levels of these important fats. The existing tools to measure how much omega-3 fat a person has are time-consuming and not practical to use in healthcare clinics. Therefore, a diagnostic test that is quick and easy to use is needed. The OmegaSTAT kit prototype has been developed by Pivotal Therapeutics to quickly measure the level of omega-3s in a person. What we don’t know is which blood fraction is best to use with the OmegaSTAT kit. Our work will look at different blood fractions and compare the OmegaSTAT results against existing tools. This work has incredible potential to public health by quickly identifying people who have low levels of omega-3s.

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Faculty Supervisor:

David Mutch

Student:

Shannon Klingel

Partner:

Pivotal Therapeutics

Discipline:

Food science

Sector:

Pharmaceuticals

University:

University of Guelph

Program:

Accelerate

Cross-sector partnerships for implementing sustainable community plans: comparison between a Canadian city and international communities to determine drivers for partners to remain in the partnerships

The project involves the identification of a Canadian community to be compared with Barcelona (Spain), Bristol (UK) and other two international communities, all experienced cities on sustainability with more than 100 partners including businesses, NGOs, academia and the public sector. The Canadian community must comply with certain criteria to make findings comparable with the international communities. The information to be collected is about the drivers for the partners to join and remain in a partnership for sustainability, a key for policy makers and practitioners in the design of sustainability plans and partnerships for reaching sustainability goals. ICLEI Canada will benefit from this research by having access to information from four highly recognized communities and by comparing them to one of its members as a benchmark for the improvement of their sustainability initiatives. Furthermore, the findings will be generalizable information that will help improve their products and services.

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Faculty Supervisor:

Amelia Clarke

Student:

Eduardo Ordonez

Partner:

ICLEI Canada

Discipline:

Environmental sciences

Sector:

Environmental industry

University:

University of Waterloo

Program:

Canadian Science Policy Fellowship

Genomics profiling of peritoneal mesothelioma and patient-derived xenograft models for in vivo biomarker validation

Peritoneal Mesothelioma (PM) is a rare type of cancer affecting the protective membrane surrounding the abdominal cavity and the second most common type of mesothelioma, consisting about 10-20% of the diagnosed cases. The underlying cellular and molecular mechanisms of peritoneal mesothelioma pathology are greatly understudied. In this proposal, we aim to enhance the current knowledge of PM pathogenesis and explore therapeutic treatments for it. To this end, we aim to establish a working group that combines pertinent and unique expertise in the areas of surgery, pathology, genomics, xenografting and biology. This collaborative team of researchers will collect and perform a pathology review on an initial cohort of PM tissues with good clinical records using state-of-the-art high-throughput DNA, RNA, and protein sequencing. We also aim to generate an in vitro PM patient-derived xenograft mouse model that can recapitulate the tumor in vivo for drug screening and testing for safety, response, and efficacy in collaborations with our biotech partner.

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Faculty Supervisor:

Yuzhuo Wang, Colin Collins

Student:

Raunak Shrestha, Noushin Nabavi, Jun Hao

Partner:

iProgen

Discipline:

Medicine

Sector:

Pharmaceuticals

University:

University of British Columbia

Program:

Accelerate

Development of negamycin, a novel class of antibiotic for Gram-negative bacterial infections

Antimicrobial resistance threatens effective prevention and treatment of microbial infections. Over two million hospitalized patients acquire infection from antimicrobial resistant microbes resulting in more than 23,000 deaths in North America. Therefore, development of a novel class of antimicrobials is in urgent need. The goal of our research project is to develop a novel antibiotic for the treatment of drug-resistant bacterial infections. This antibiotic targets ribosome to inhibit protein synthesis. We are introducing chemical modifications and analyzing antimicrobial activity in order to select a more potent analogue of this antibiotic for clinical use. The company is in developing stage and will benefit from the academic expertize and established experimental set-ups to speed up their research program.

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Faculty Supervisor:

John Rohde

Student:

Hirendrasinh Parmar

Partner:

Appili Therapeutics Inc

Discipline:

Biology

Sector:

Life sciences

University:

Dalhousie University

Program:

Accelerate

Pelvic Floor Health and Sexual Well-Being in Women Across the Lifespan

The promotion and maintenance of women’s pelvic floor health is a growing concern as pelvic disorders affect a substantial number of women and their prevalence is expected to increase as a result of Canada’s aging population. Pelvic floor disorders go beyond their physical consequences as they can negatively impact women’s psychological, sexual, and social quality of life. Evidence strongly suggests pelvic floor muscle training (PFMT) can contribute to the promotion and maintenance of pelvic floor health and to the treatment of symptoms associated to pelvic floor disorders. However, the associations between women’s pelvic floor health and sexual health across the lifespan require further attention from research and the factors that contribute to adherence of PFMT are still poorly understood. Improving evidence-based knowledge in these areas is critical in the development interventions and products aimed at maintenance and promotion of pelvic health and treatment of pelvic floor disorders.

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Faculty Supervisor:

Elke Reissing

Student:

Emilie Gravel, Heather VanZuylen

Partner:

Standard Innovation Corporation

Discipline:

Psychology

Sector:

Medical devices

University:

University of Ottawa

Program:

Accelerate

Characterization and Improvement of Interfacial Properties of Cathode Materials for Rechargeable Hybrid Aqueous Batteries

Using surface characterization techniques, the relationship between the surface hydrophilicity level of the positive electrode and the electrochemical performance of a rechargeable aqueous battery system will be investigated. Oxygen is generated during the battery operation due to the decomposing of water, the solvent for the electrolyte, and may cover the surface of the positive electrode, thus hinder the battery operation. It is postulated that in the case of hydrophilic cathode, the oxygen bubbles created inside the battery will not prevent the wetting of the positive electrode with the aqueous electrolyte. Hence, a more hydrophilic electrode material will enhance the cycling stability and eliminate capacity fading of the battery system. Effect of different components of the positive electrode and the electrolyte will be investigated using surface characterization and electrochemical techniques in this research.

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Faculty Supervisor:

Pu Chen

Student:

The Nam Long Doan

Partner:

Positec

Discipline:

Engineering - chemical / biological

Sector:

Nanotechnologies

University:

University of Waterloo

Program:

Accelerate

Developing Strategic Planning Tools to Support Forest Industry Transformation

Much of the management theory taught in today’s classrooms is focused on consumer-based, growth businesses rather than natural resource-based, cyclical industries. This study will examine how natural resource industries, such as forestry, recognize and adapt to structural (permanent) challenges in their market environment. The research will have three main components: first, using publically available information sources, it will inventory which strategic actions North American and European forestry companies have taken over the past decade to acclimate to their changing business environment. Second, it will identify the most relevant streams of management and strategy literature, suggesting modifications to incorporate the needs of natural resource firms. Third, it will survey industry decision-makers to test the newly-updated theories, and develop comprehensive yet straightforward tools to aid industry in recognizing and interpreting market signals. The resource-based partner company has expressed an interest in using the strategic planning tools developed by this project to evaluate and validate its evolving corporate strategy.

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Faculty Supervisor:

David Cohen

Student:

Alice Palmer

Partner:

Catalyst Paper Corporation

Discipline:

Forestry

Sector:

Pulp and paper

University:

University of British Columbia

Program:

Accelerate

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