Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

31133 Completed Projects

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Projects by Category

Décomposition de Dantzig-Wolfe pour l’optimisation basée sur des modèles de choix discret avancés

De nombreux problèmes décisionnels réels issus des domaines des transports, de la logistique et de l’administration publique partagent une structure commune dans laquelle un décideur cherche à adopter des politiques permettant d’optimiser un objectif qui dépend de la réaction d’une population. Pour adéquatement formaliser ce type de problème, l’hétérogénéité des préférences et des objectifs des individus doit être fidèlement modélisée. Ceci est généralement rendu possible par l’intégration de modèles de choix discrets avancés dans un problème d’optimisation. Cette intégration produit toutefois des problèmes stochastiques difficiles qui ne peuvent généralement pas être résolus à l’optimalité par des méthodes existantes dans le cas de problèmes de grande taille. Pour faire face à cette limitation, la structure de problèmes d’optimisation importants basés sur des modèles de choix discret sera analysée et des méthodes de décomposition mathématiques de la littérature, en particulier la décomposition de Dantzig-Wolfe, seront adaptées pour en permettre une résolution efficace.

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Faculty Supervisor:

Emma Frejinger

Student:

Partner:

École polytechnique fédérale de Lausanne

Discipline:

Mathematics

Sector:

Education

University:

Université de Montréal

Program:

Globalink Research Award

Ocean Waves to Power Data Monitoring Buoys

This project aims to design sustainable new microsystems to power data monitoring buoys that can provide a sustainable power source using the ocean waves dynamics. The proposed project will result in significant advances in three long-standing challenges in energy harvesters-based micro devices powering the data monitoring buoys using the ocean waves. These include low frequencies of the ocean waves, mechanical failures due to (high mechanical stress) of the ocean waves, and the efficiency of the energy harvesters-based microdevices.

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Faculty Supervisor:

Mohammad Al Janaideh;Lihong Zhang;Lihong Zhang

Student:

Partner:

Net Zero Atlantic

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

Memorial University of Newfoundland

Program:

Accelerate

3D printed bio composites for EMI shielding application

Electromagnetic (EM) waves are becoming more prevalent due to the rapid development of electronics, which pose serious risks to human health, electric devices, and the environment1,2. In order to overcome the above problems, engineering and fabrication of multifunctional EM shielding materials are indispensable. Thus, recently, a wide spectrum of materials ranging from metals to soft conductive materials such as hydrogels, with the majority being focused on exploring EM interference (EMI) shielding materials with lightweight properties, flexibility, and excellent shielding performance3–7. However, due to the high electrical conductivity of the mentioned materials, resulting in high impedance mismatches, these shields reflect a main portion of the incident wave, producing secondary pollution. So, developing high-efficiency EMI shielding with a strong absorption performance remains a tremendous challenge. However, EMI shielding based on an absorption mechanism can be effectively enhanced by controlling the structure (macro and micro-scale) of the shields8,9. By constructing three-dimensional (3D) porous conductive networks and controlling the macro-scale structures, an efficient strategy can alleviate the impedance mismatching and result in lower shielding effectiveness by reflection (SER) value10,11.
Hence, two major approaches are available to improve shielding effectiveness (SE) and control the shielding mechanism.

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Faculty Supervisor:

Mohammad Arjmand

Student:

Partner:

Harvard University

Discipline:

Engineering

Sector:

Education

University:

The University of British Columbia - Okanagan

Program:

Globalink Research Award

Targeting mitochondrial efficiency to promote resilience of dopamine neurons

Parkinson’s disease (PD) is a devastating neurodegenerative disease impacting the nervous system and resulting in a wide range of symptoms including characteristic motor impairments such as tremor, slowed movement and muscle rigidity. It is an age-related disease affecting 1% of the population over the age of 60. Although symptomatic treatments are available, there are no disease-modifying therapies. My project will target the underlying causes of neuron loss in PD, which has been linked to mitochondrial dysfunction. Amongst the most affected neuronal populations affected in PD are dopaminergic neurons of the substantia nigra (SNc). These neurons produce dopamine as a chemical messenger and their receptors are key regulators of brain circuits controlling movement. My project will have as a main goal to identify small molecules capable of improving the resilience of dopaminergic neurons by targeting mitochondrial energy production and oxidative stress. For this, experiments will be performed in a system of primary mouse dopamine neurons, together with advanced microscopy techniques and image analysis strategies. We will specifically test the hypothesis that molecules improving mitochondrial efficiency will increase resilience by reducing chronic oxidative stress.

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Faculty Supervisor:

Louis-Eric Trudeau

Student:

Partner:

St George's, University of London

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Pharmaceuticals

University:

Université de Montréal

Program:

Globalink Research Award

Deployment of flexible CAD teamwork: a battery swapping mechanism case study

Product lifecycle management has always been promising. But achieving fully connected data, people, and processes may seem daunting for most SMEs. Spiri Robotics is a vibrant company with strong software engineering roots. They run distributed, remote operation in parallel in several North American cities using state-of-the-art versioning, testing and deployment tools for their code. However, their mechanical design files (CAD) are centralised and manually managed. With their academic and commercial collaborations expending, this a limiting factor and a risk they would prefer to avoid. The goal of this project is to use the design of a novel battery swapping station to deploy and validate a PLM vault architecture. Design and tests will be conducted in simulations, from CAD to flight simulators, integrating design for additive manufacturing considerations up to a physical prototype to validate the product design and its design process.

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Faculty Supervisor:

David St-Onge

Student:

Partner:

Spiri Robotics

Discipline:

Engineering

Sector:

Manufacturing

University:

École de technologie supérieure

Program:

Accelerate

Deciphering the immunosuppressive functions of viral glycoproteins

Embedded in the surface of a virus, are different types of proteins that the virus uses to enter a host cell. These so-called viral glycoproteins are pivotal targets of the host antibody response to fight a viral infection. In recent decades, it has become clear that certain viral glycoproteins have evolved clever ways to suppress the immune activators on the host cell. Certain regions on viral glycoproteins directly contribute to immune evasion by misdirecting antibody responses, affecting intracellular signaling and hampering cytokine production. However, the molecular mechanisms that underlie these immunomodulatory functions of viral glycoproteins at initial stages of infection remain elusive. During his 9-month project, Bart will seek to elucidate how immunosuppressive motifs on viral fusogens from Ebola, HIV-1 and other retroviruses, are able to modulate immune activators present on the cell surface. Bart will focus on identifying the targeted immune cell populations and cell surface receptors that participate in immune suppression via binding to ISRs using flow cytometry, immunological assays to measure cytokine expression profiles and pulldown-MS work to decipher protein-protein interactions.

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Faculty Supervisor:

Jeffrey E. Lee

Student:

Partner:

Leiden University

Discipline:

Life Sciences

Sector:

Education

University:

University of Toronto

Program:

Globalink Research Award

Dégradation aérobie du mazout diesel n°2, bunker diesel n°6 et de l’huile à moteur

En 2010, au Québec, 73 % des terrains recensés par le Système de gestion des terrains contaminés (Système GTC), affichent une contamination de nature organique (Hébert et Bernard, 2013) Actuellement, les techniques de dégradation chimique et/ou biologique sont largement utilisés dans l’industrie, mais les résultats sont souvent décevants pour les hydrocarbures les plus lourds (Bunker diesel n°6) (Nyman, Klerks et Bhattacharyya, 2007) (Coulon et al., 2010) (Coulon et al., 2012). Le projet ci-présent vise : (1) l’optimisation des méthodes chimiques et biochimiques in situ traditionnelles de dégradation aérobie des combinaisons d’hydrocarbures, lourds et légers – bunker diesel n°6 , mazout diesel n°2, huile à moteur-; ceci par la détermination des séquences et des ratios bactéries/champignons/oxydant chimique les plus adaptés selon le contexte géochimique des terrains à l’étude; (2) la caractérisation des «voies» de dégradation des contaminants d’origine ainsi que l’atténuation de la toxicité des métabolites associés.
La finalité pour l’entreprise étant la commercialisation des «formules» de rémédiation développées

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Faculty Supervisor:

Alfred Jaouich

Student:

Partner:

Enutech

Discipline:

Earth science

Sector:

Professional, scientific and technical services

University:

Université du Québec à Montréal

Program:

Accelerate

Hydrogen Storage and Transportation

Without doubt, hydrogen will be a significant component of future worldwide energy supply. The main issue that hampers the use of hydrogen is related to its storage and transportation which currently uses costly high pressure or very low temperature to transport and store hydrogen. Therefore, there is an urgent need to provide a safe, efficient, and economically viable hydrogen transport and storage technology. Liquid organic compounds can store hydrogen in their structure and release it wherever there is a need for hydrogen. The technology requires efficient catalysts for storing and releasing of the hydrogen to and from the liquid organic. This project will use new, efficient catalysts as a basis to assess the techno-economic viability of the proposed hydrogen storage and transportation technology.

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Faculty Supervisor:

Kevin Smith

Student:

Partner:

Springboard Atlantic Inc.

Discipline:

Engineering

Sector:

Green/Alternative Energy; Clean Technology; Energy and Utilities

University:

The University of British Columbia

Program:

Accelerate

The LARP1 homolog Slr1p controls the stability and expression of proto-5’TOP mRNAs in fission yeast

Messenger RNAs (mRNAs) need to be decoded and translated into proteins in our bodies. This process must be tightly regulated by RNA-binding proteins such as LARP1. This protein is found in several organisms and by regulating mRNA translation it also regulates cell growth, but its function is poorly understood. LARP1 has been found in higher-than-normal amounts in cancerous cells therefore it is thought to lead to tumor progression and poor patient outcomes. Studying LARP1 in human cells has been challenging because of the complexity of the human system. Simpler organisms such as fission yeast also have a LARP1 protein called Slr1p, whose study has been informative towards understanding human LARP1 function. One aspect of the research in this field that has not been explored yet is how LARP1 binds mRNAs during mRNA translation. Using the simpler yeast Slr1p, we will employ Selective Translation Complex Profiling and Sequencing to identify mRNA sites where Slr1p interacts with the translation initiation machinery on its target mRNAs. This will help delineate the various confounding mRNA binding modes of LARP1 family of proteins and their functions under different circumstances and disease states.

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Faculty Supervisor:

Mark Bayfield

Student:

Partner:

University of Cambridge

Discipline:

Life Sciences

Sector:

Education

University:

York University

Program:

Globalink Research Award

Characterizing and modelling products recovered from gold-bearing mine tailings using a novel clean technology

AJ Min Inc. is developing a novel technology to recover gold from tailings material. The technology requires little energy, little to no reagents, and little to no additional water. Past testwork has indicated that this technology can recover significant amounts of gold from some tailings material, and that the recovered gold can be upgraded. This project will build on previous testwork to characterize the test products and develop metallurgical models to predict and improve performance. In addition, a fully automated pilot unit will be assembled, programmed, and tested.

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Faculty Supervisor:

Bern Klein

Student:

Partner:

AJ Min Inc

Discipline:

Engineering

Sector:

Mining

University:

The University of British Columbia

Program:

Accelerate

Formulation et évaluation de liants polymères écoresponsables pour la fabrication additive de céramiques

De nos jours, les pièces en céramique de grande précision sont généralement obtenues par moulage par injection, un procédé rentable pour la production à grande échelle, mais non viable pour la production de petites séries de pièces telles que les pièces d’horlogerie. Il est donc nécessaire de trouver de nouvelles techniques pour ce type de production. Ce projet a pour objectif d’intensifier la recherche sur les nouveaux liants biopolymères et les procédés d’impression, reconnus comme étant l’avenir en matière de fabrication, pour aboutir à des pièces fonctionnelles intégrables directement dans les systèmes d’horlogerie. Ce projet pluridisciplinaire faisant appel à trois institutions académiques (spécialisées respectivement en polymères, céramiques et contrôle non destructif) et deux partenaires privés des secteurs de l’horlogerie et de la fabrication additive. Un tel consortium permettra des avancées significatives en formulation de liants et dans la maîtrise des procédés de fabrication additive pour les céramiques.

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Faculty Supervisor:

Pascal Vuillaume;Saïd Elkoun

Student:

Partner:

FABLAB Inc.

Discipline:

Engineering

Sector:

Manufacturing

University:

Cégep de Thetford

Program:

Accelerate

Developing and implementing novel microfluidic scanning probes for spatial profiling of heterogenous tumor samples via a multi-omics approach

The aim of the project is to develop microfluidic technologies to analyse heterogenous tumor tissues/cells via a multi-modal approach using spatial genomic, transcriptomic and proteomic data. The resulting data obtained could be used for prognostics, diagnostics and prediction of therapies. Microfluidic scanning probes (MFP) technology, invented by the Kaigala team while at IBM Research in Zurich, that implement assays in a localised and rapid manner, is able to efficiently subtype tumor sections and is a lucrative alternative to traditional methods. We will build on TRACERx Renal study and try to improve spatio-temporal resolution in renal cell carcinoma sections by spatially profiling clonal populations within the sample using clinically annotated mutation and expression profiles. Gene-transcript data will be preprocessed using independent component analysis (ICA) strategies and its interactions will then be integrated through multiomic bioinformatic strategies. The overall objective is to specifically locate clones along with their evolutionary pathway and determine their correlation with morphological features, thus helping to bridge the gap between tumor profile and therapy.

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Faculty Supervisor:

Govind Kaigala

Student:

Partner:

Goethe University Frankfurt

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Nanotechnology; Life Sciences (not health)

University:

The University of British Columbia

Program:

Globalink Research Award

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Mitacs — Return on Innovation

Mitacs is funded by the Government of Canada, the Government of Alberta, the Government of British Columbia, Research Manitoba, the Government of New Brunswick, the Government of Newfoundland and Labrador, the Government of Nova Scotia, the Government of Ontario, Innovation PEI, the Government of Quebec, the Government of Saskatchewan, and the Government of Yukon.