Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

13270 Completed Projects

1072
AB
2795
BC
430
MB
106
NF
348
SK
4184
ON
2671
QC
43
PE
209
NB
474
NS

Projects by Category

10%
Computer science
9%
Engineering
1%
Engineering - biomedical
4%
Engineering - chemical / biological

A rapid detection test (RDT) to determine surface contamination by the SARS-CoV2 virus

The residual bacterial and viral contamination that remains on surfaces after cleaning in healthcare and palliative care settings is particularly lethal during a pandemic. Due to inevitable overcrowding and long shift hours, slipups occur. A technique to monitor surface cleanliness, and particularly to detect the presence of SARS-CoV2, is required to ascertain contamination and, if necessary, refine cleaning processes. We will develop a swab-based rapid detection test (RDT) kit to determine the presence of the SARS- CoV2 virus on surfaces. The RDT is based on a proven particle plasmon resonance sensing method using gold nanoparticles commercialized by our industry partner Genemis Labs. During our research, we will modify this sensing technique and make it specific to SARSCoV2 virus using antibodies specific to its viral surface proteins. Gold nanoparticles will be functionalized with antibodies and stabilized in a colloidal suspension that, along with a single-use sample processing apparatus and a portable colorimeter, will be used to detect colour changes that quantify relative surface viral load. The RDT will provide a quick method to monitor the presence of SARS- CoV2 and verify a surface cleaning procedure, thereby
diminishing infection spread and standardizing best practices across facilities.

View Full Project Description
Faculty Supervisor:

Ishwar Puri;Rakesh P Sahu

Student:

Sarah Mishriki;Srivatsa Aithal

Partner:

Genemis Laboratories

Discipline:

Engineering - biomedical

Sector:

Manufacturing

University:

McMaster University

Program:

Accelerate

Cellular inflammatory and anti-viral effects of BOLD-100, a novel therapeutic agent in development for COVID-19

Bold-100 is a promising new drug that has been studied as a treatment for cancer. Because of the way it works in cells, there is reason to believe that it may also help protect against infections with viruses like SARS-CoV2 (the cause of COVID-19). The purpose of this project is to study the effects of Bold-100 on cells derived from the human intestine, which are susceptible to SARS-CoV2 infection, to help determine the way the drug effects normal cellular functions and their response to viral infections. The results will help to define the potential of Bold-100 as an antiviral drug, as well as its potential uses for other diseases, including intestinal cancers and inflammatory bowel disease.

View Full Project Description
Faculty Supervisor:

Ted Steiner

Student:

William Rees

Partner:

Bold Therapeutics

Discipline:

Medicine

Sector:

Professional, scientific and technical services

University:

University of British Columbia

Program:

Accelerate

Ultraviolet inactivation of Covid-19

Many major municipalities rely on ultraviolet (UV) disinfection of their drinking water and wastewater to protect their citizens and the environment. The novel coronavirus, Covid19, has been detected in water, and may be transmitted by improperly treated wastewater and drinking water. It is important that the sensitivity of Covid19 to UV be measured, in order to ensure adequate UV disinfection. This project will develop methods to accurately assess the UV sensitivity of coronaviruses, and measure the UV sensitivity of coronaviruses in water. These data will allow non-pathogenic coronaviruses to be used as safe surrogates for assessing UV systems. The methods will be transferred to third-party labs that will use them to evaluate pathogenic Covid19 virus.

View Full Project Description
Faculty Supervisor:

Marc Aucoin

Student:

Scott Boegel

Partner:

Trojan Technologies

Discipline:

Engineering - chemical / biological

Sector:

University:

University of Waterloo

Program:

Accelerate

Economic Impacts and Influence of COVID-19 on Syrian Refugee Settlement and Integration in Rural Canada

The research will highlight the COVID-19 related economic and social challenges faced by Syrian Refugees who have settled in Rural Canada. These new residents have settled, started to adjust to life in Canada, and have suddenly found themselves challenged by economic and social uncertainty brought about by COVID-19. The results of this research will help local governments and community organizations, in addition to anyone planning settlement and integration activities, to better understand how refugees are being impacted, their priorities, and what supports and services are critical to ensuring the health and economic well being and resilience of new refugees. The study will identify economic impacts associated with COVID-19 and will offer strategies and approaches aimed to assist these new residents.

View Full Project Description
Faculty Supervisor:

Wayne Caldwell

Student:

Rana Telfah

Partner:

Gateway Centre of Excellence in Rural Health

Discipline:

Environmental sciences

Sector:

Professional, scientific and technical services

University:

University of Guelph

Program:

Accelerate

Investigating Photocatalysis using Visible Light for inactivation of the virus SARS-CoV-2

Due to the SARS-CoV-2 pandemic, there is: 1) a worldwide shortage of Personal Protection Equipment (PPE) for frontline Health Care Professional; and 2) a demand for products which can reduce the risk of contracting SARS-CoV-2. We plan to assess the use of titanium-based particles to inactivate viruses and bacteria using visible light. The particles can be used in wide range of other applications including 1) air filtration systems such as ventilators, air purifiers; 2) water filtration systems such as water purifiers; and 3) surface cleaning systems.

View Full Project Description
Faculty Supervisor:

Horacio Bach

Student:

Maria Marta Ayup

Partner:

Photonclean

Discipline:

Medicine

Sector:

Professional, scientific and technical services

University:

University of British Columbia

Program:

Accelerate

COVID-19 and the Future of Ontario’s Agricultural Workforce

The Canadian agricultural sector has been particularly effected by the outbreak of the COVID-19 pandemic. Due to shortages in agricultural labour, the sector relies on the annual arrival of migrant workers, which in 2020 was disrupted due to the travel restrictions and quarantine orders enacted to fight the spread of this virus. As a result, many agricultural employers are struggling to find workers to cultivate their crops. This research initiative is designed to address this problem. In partnership with the Ontario Cooperative Association (OCA), the researchers will interview Ontario farmers to explore the full impact of these labour disruptions on their financial wellbeing, which will help the OCA’s members to communicate their needs to the federal and provincial. Additionally, the researchers will conduct an international search for strategies to better prepare the sector for future events which may similarly disrupt the agricultural labour supply.

View Full Project Description
Faculty Supervisor:

Ryan Gibson

Student:

William Louis Helps

Partner:

Ontario Co-operative Association

Discipline:

Environmental sciences

Sector:

Other services (except public administration)

University:

University of Guelph

Program:

Accelerate

Exploring and Improving Self-supervised Methods for Large-scale Video Recognition

With the advancement of modern technology, especially the increase in network speed, videos are taking more and more important places among media types. With vast potential applications, video recognition has received great attention. However, video recognition is a non-trivial task: a lot of training data are needed for complicated neural networks, but annotated data are hard to acquire. As a result, there is a growing tendency to bank on self-supervised learning approaches that can make use of unlabeled data. Some results have been made but it is still a pretty preliminary topic with a lot of room to improve. This project aims to dig into this topic, design and experiment more efficient algorithms and train on larger-scale datasets. The expected result would be an improved large-scale video recognition pretrained model that achieves competitive performance.

View Full Project Description
Faculty Supervisor:

Animesh Garg

Student:

Keyu Long

Partner:

Layer 6 AI

Discipline:

Computer science

Sector:

Professional, scientific and technical services

University:

University of Toronto

Program:

Accelerate

Determining the antiviral properties and mechanism of actions of BOLD-100 against SARS-CoV-2 in 2D and 3D cell culture systems

BOLD-100 is a promising new clinical stage therapeutic, originally developed for the use as a cancer treatment. The mechanism of action for BOLD-100 suggests that this therapeutic might also protect against infections with viruses, including coronaviruses like SARS-COV-19. The purpose of this project is to test the antiviral efficacy of BOLD-100 against SARS·COV-19 in 20 and 30 cell culture models, and then investigate the mechanism of action. These results will help define BOLD-100 as an antiviral treatment and support clinical investigations into BOLD-100 for the treatment of COVID-19.

View Full Project Description
Faculty Supervisor:

François Jean

Student:

Amy Short

Partner:

Bold Therapeutics

Discipline:

Biology

Sector:

Professional, scientific and technical services

University:

University of British Columbia

Program:

Accelerate

The development of SARS-CoV-2 lateral flow strip using genetically engineered viral antigen

While various community transmission mitigation tactics are being employed in regions across Canada, including stay home mandates, bans on public congregations, and provincial lockdown, public health experts and scientists agree that widespread availability of testing for COVID-19 would aid efforts in more accurately tracking the virus’ spread.
This project aims to develop a more sensitive serology test strip to detect COVID-19 positive patients. By utilizing genetic engineering technique, we will develop sensitive and accurate test strip which detects COVID-19 patient at early stage. This economical and easy-to-use test strips will provide quick (15 minutes) and accurate results. This project will produce more effective and affordable testing to help these people by reducing the number of infected patients at healthcare facilities, and by helping society to return to more normal operations.

View Full Project Description
Faculty Supervisor:

Fei Geng

Student:

Saeed Mohammadi

Partner:

Thinkari Research Inc

Discipline:

Engineering - mechanical

Sector:

Professional, scientific and technical services

University:

McMaster University

Program:

PGX-processed yeast beta-glucans as an inhalable immunomodulating therapeutic for COVID-19 patients

While many people who acquire COVID-19 experience only minor symptoms or are completely asymptomatic, others (~20% of patients) experience a severe form of the disease associated with a phenomenon called a cytokine storm, an undesirable immune response that ultimately results in the deposition of fibrotic tissue in the lungs that causes the breathing difficulties and ultimately death in severe COVID-19 cases. There are to-date no therapeutics that have been demonstrated to relieve such cytokine storms, or avoid the resulting changes in the lung tissue, observed in severe COVID-19 patients. In this project, we seek to expand on preliminary results from an ongoing collaboration between the labs of Kjetil Ask and Todd Hoare at McMaster University and our industry partner Ceapro regarding the utility of yeast beta-glucan particles processed using Ceapro’s pressurized gas expanded liquids (PGX) technology for modulating the immune system in without any added drug. PGX processing both purifies and expands the raw yeast beta-glucan product to both remove components that can cause undesirable side-effects and reduce the density of the material to make the particles easier to inhale directly into the targeted lung tissue.

View Full Project Description
Faculty Supervisor:

Kjetil Ask;Todd Ryan Hoare

Student:

Safaa Naiel;Aaron Hayat;Nate Dowdall;Spencer Revill

Partner:

Ceapro

Discipline:

Sector:

Manufacturing

University:

McMaster University

Program:

Accelerate

Therapeutics and Catalysts for the COVID-19 Pandemic

Overcoming the COVID-19 pandemic will require a multi-pronged therapeutic approach that will draw on the expertise of biochemists, virologists, medicinal chemists and synthetic chemists. First-line tactics directly attack the virus itself. This will be done in the form of small-molecule antivirals that inhibit the development of virus particles during infection and replication. Secondary effects of COVID-19 include bacterial infection that sets in when the lungs undergo inflammation and fibrosis, which is a significant contributor to mortality. The team assembled through Carleton (Professor Jeff Manthorpe PI) is well set up through its existing 16-month relationship with Total Synthesis Ltd. (TSL) to work on the necessary synthetic and medicinal chemistry and associated catalyst development to make these challenging drug candidates, which will be screened for antiviral and antibacterial properties in biochemistry labs at McMaster U and uOttawa.

View Full Project Description
Faculty Supervisor:

Jeffrey Manthorpe

Student:

Sepideh Sharif;Mathieu Morin;Monica Gill;Nalin Chandrasoma;Ryan Sullivan

Partner:

Total Synthesis Ltd

Discipline:

Chemistry

Sector:

Manufacturing

University:

Carleton University

Program:

A 20 minute molecular diagnostic of COVID-19 within a “swab”

The research project will find optimal conditions for instrument-free, fast, and sensitive/specific detection of pathogen (COVID-19). The project is composed in two units(IU), each module within IU is offering independent technical solution for the current bottleneck in diagnostics industry. The first module is temperature-based denaturation of biological sample, coupled with nucleic acid-based detection (IU1). The second module is composed of specific amplification of biomarker for intended target/s, (instrument free) and the last module is colorimetric detection of amplified biomarker. These steps are essential for building universal diagnostic device which is projected to haveas high quality performance, as current state-if-the-art techniques, but is also fast (20 minutes) and does not require any additional technological setting. The partner organisation will use the technical solution provided by this project and generate it’s own, in-house, nucleic acid isolation/purification/detection techniques.

View Full Project Description
Faculty Supervisor:

Ivan Brukner;Matthew Oughton

Student:

Alex Resendes

Partner:

Pharmascience

Discipline:

Biology

Sector:

University:

McGill University

Program:

Accelerate