Lactating dairy cows have extensive embryonic loss, but the mechanisms that lead to this failure to maintain pregnancy are not clearly understood. It is suggested that high-producing dairy cows are marginally deficient in nutrients such as Vitamin B complex molecules, selenium etc., which are positively associated with health and reproduction. The goals of the project are to determine the effect of a rumen-protected vitamin B complex supplementation (VIT) compared with control diet containing no supplement (CON) on: milk production and plasma levels of BHBA, NEFA and acute phase proteins; ovarian follicle growth and plasma levels of major steroids; and uterine gene expression of target transcripts related to embryo development, immune function and cellular adhesion on day 15 of cycle or pregnancy. We hypothesize that supplementing vitamin B molecules will improve follicle growth and ovarian
steroid synthesis as well as improving the make-up of expression of key transcripts pivotal to pre-attachment embryonic development.
JEFO Nutrition Inc
University of British Columbia
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