Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Imaging of cerebral perfusion (the delivery of blood to a capillary bed in the brain tissue) is significant for diagnosing a variety of diseases. There are multiple challenges associated with perfusion imaging which significantly limits the quality of cerebral perfusion images. I am planning to develop a novel approach of cerebral perfusion magnetic resonance imaging (MRI) using hyperpolarized (HP) xenon-129 (129Xe). To conduct HP 129Xe perfusion imaging, I am developing a novel HP MRI Time-of-Flight (TOF) pulse sequence. This imaging technique allows for the acquisition of perfusion images with a high signal-to-noise ratio and contrast-to-noise ratio. Furthermore, this imaging methodology allows for the acquisition of quantitative perfusion images in less than 20 s. HP 129Xe TOF imaging has the potential to overcome the challenges of current cerebral perfusion imaging and become a powerful tool for early-stage diagnosis of perfusion related neurological diseases such as Alzheimer’s and Parkinson diseases. This will allow for better treatment planning, which will be beneficial for modern clinical practice. Furthermore, HP 129Xe TOF imaging can significantly improve the understanding of the mechanism of perfusion-related diseases, which will allow for the development of highly efficient treatments for further translation into clinics.
Thunder Bay Regional Research Institute
Find the perfect opportunity to put your academic skills and knowledge into practice!Find Projects
The strong support from governments across Canada, international partners, universities, colleges, companies, and community organizations has enabled Mitacs to focus on the core idea that talent and partnerships power innovation — and innovation creates a better future.