Glioblastoma (GBM), the most common and deadly form of primary brain cancer in adults. After diagnosis, GBM patients undergo standard therapy, including surgery, chemotherapy and radiation therapy. Unfortunately, disease relapse is inevitable and patients face a median survival of less than 15 months. A small population of tumor cells, known as brain tumor initiating cells […]

The development of environment-friendly freezing technologies to contaminated water is a potential solution for water treatment in regions with cold weather conditions and vulnerable to anthropogenic impact. The results of laboratory tests fulfilled by Core Geoscience Services Inc. on the removal of mine-impacted water species through ice formation along with other publicly available data will […]

DoseBiome has developed a new probiotic that targets several aspects of oral health: dental caries, periodontal diseases, and halitosis. This project aims to understand the exact mechanism of our probiotic’s inhibitory properties against the pathogens associated with the above diseases. DoseBiome is a new start-up in the probiotic/microbiome health sector, and this project will allow […]

Recent studies have called into question the Linear No Threshold (LNT) model of radiation protection, which predicts a linear increase in cancer risk with low-dose radiation exposure. However, current experimental evidence suggests that low-dose radiation (LDR,

Cancer will affect 2 in every 5 Canadians in their lifetime, with just over 25% representing new breast cancer diagnoses in women. Despite significant progress in the treatment of the most common cancer in women, resistance to chemotherapeutic agents remains a consistent obstacle in terms of the successful treatment of many types of breast cancers. […]

Mitochondria are critical producers of energy and are the platform for various metabolic reactions that support cellular health. Mitochondria suffer from a variety of damage as a consequence of housing these reactive pathways. In order for cells and organisms to survive this damage, dysfunctional mitochondria are removed from the cell in a process termed mitophagy. […]

Coming into force in October 2019, amendments to the Canadian Cannabis Regulations will introduce guidelines governing the legal production and sale of cannabis-infused extracts, edibles, beverages and topicals. These new products are at the forefront of the natural health product (NHP) and consumer packaged goods (CPG) industries, but challenges associated with their formulation, production and […]

Although recreational and medicinal marijuana is legal in Canada regulations limit the content of certain cannabinoids, such as ?9-tetrahydrocannabinol (?9THC) in commercially grown strands. With close collaboration with our industrial partner Plantbiois Ltd., this research project will develop methods to produce ?9THC by synthetic conversion from highly abundant cannabinoids in unregulated, low THC strains. We […]

Using genomics in clinical care has the potential to treat patients more efficiently. There have been a number of recent discoveries of genomic assays that can guide treatment. However, most genomic data is generated in a research setting and useful health data only in a clinical setting. Translating potential genomic research into a clinical setting […]

Drug resistance of medically relevant microorganisms poses a grave threat to human health and has severe economic consequences. Fungal pathogens pose an additional complication as they are closely related to their human host. Current therapies to treat fungal infections are limited and drug resistance has already emerged in the clinic. We have conducted extensive research […]

Currently, the traditional use of the dye-sensitized solar cell (DSSC) is well-known in the science community as an effective photovoltaic technology, where it works best in diffuse lighting conditions. With the insights brought from this research project, the DSSC can also be transformed into an optically sensing motion sensor based on the dye utilized within […]

Natural extracts have potential as anti-cancer therapeutics. These botanical materials are well tolerated and are safe to be given as supplements over long periods of time. This project aims to provide scientific and clinical validation of these extracts for their anticancer effects and sensitization of cancer cells to standard chemo regiments. Synthite Industries Inc., a […]