Discovery of antibodies against challenging membrane protein targets using microencapsulation-assisted rare clone selection

Antibody-based medicines are playing an ever increasing role in the arsenal of treatments of many diseases, from cancer to obesity to Alzheimer’s. Cell surface proteins, called membrane receptors, are considered key therapeutic targets in many of these pathologies, yet targeting them with antibodies has proven to be a challenge. Amgen British Columbia is dedicated to […]

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Investigation of New Gelation Agents

This project involves the synthesis, characterization and evaluation of new low-molecular weight gelators for cleaning up oil spills. First responders to oil spills can add these gelators to the oil / water mixture to prevent spreading of the oil before additional resources are available to clean up the spill. This project will involve collaboration with […]

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3D visualizations for neuroscience education, research, and clinical applications

As new technologies are rapidly being integrated in postsecondary institutions, the question is often where to focus investment and how to facilitate adoption of new technologies by faculty and students. The advent of an era that will increasingly rely on the use of augmented and virtual reality in the instructional arena necessitates the creation of […]

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Novel membrane mimetics in HT antibody screening and structural biology

Many therapeutic targets are proteins embedded in the membrane that surrounds the cell. Traditionally, such targets present major challenges, because they required the use of detergents to extract them from the membrane and to purify them. Such detergents can cause artefacts, hampering the development of novel therapeutics. Here we will test new methods that get […]

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Real-time measurement of the thickness swelling of modified fibreboard

Wood composite panels such as particleboard and fiber board swell when they get wet and, as a result, they are only used to make products that are used indoors. However, a new type of (modified) fibreboard has been developed that doesn’t swell when it becomes wet, which opens up the possibility of using fibreboards outdoors […]

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GIF Tools II – Advanced GeoPhysical Inversion II (Year Two)

Over the past 25 years researchers at the UBC Geophysical Inversion Facility (GIF) have generated forward modelling and inversion codes that deal with most types of data of interest to a consortium of mining companies. This proposal moves the research to applications in their corporate environments, and to advance the tools and understanding about how […]

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Centre for Operations Excellence Industry Projects 2018

The Centre for Opertations Excellence Industry Projects 2018 consists of seven sub-projects sponsored by five different industry partners. Each sub-project represents an important challenge for its sponsor. These sub-projects include Correlating Anomaly detection for Boeing Vancouver(Boeing 1), Correlating NOTAMs with airport disruption for Boeing Vancouver (Boeing 2), Using Wifi data to measure process times at […]

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Blockchain-based Consent Management for Personalized Medicine

This multidisciplinary project will investigate the social, data, and technical issues surrounding design and implementation of a blockchain-based solution for the management of consent for the use of individuals’ “omics” data in medical research. Blockchains are distributed ledgers in which confirmed and validated blocks are organized in an append-only chain using cryptographic links. This project […]

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Automatic Delineation of Seismocardiogram and Gyrocardiogram Signals

The project aims at accomplishing the real-time delineation of both Seismocardiogram and Gyrocardiogram signals (which are associated with different stages of the cardiovascular cycle) and effectively extracting cardiac performance metrics (fiducial points) for use in a non-invasive portable diagnostic tool as the deviations of the either timing or amplitude can be indicative of abnormality in […]

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User experience heuristics in extended reality

We now live in a world where people can communicate, in real-time, both directly and remotely (e.g., Skype); and where new technologies (e.g., virtual reality, robots, driverless cars) are blurring the traditional lines of human-human and human-computer interactions. The digital world of industry is experiencing a revolution. Products that have traditionally been displayed on computer […]

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