Prostate cancer (PCa) is the most common form of cancer in men from developed countries, and ranks second in cancer-related deaths. The rapid recurrence of drug-resistant tumors in patients with incurable androgen-independent castrate resistant prostate cancer (CRPC-AI) underscores the need for more effective therapies. Our recent findings suggest that androgen deprivation therapy (ADT) enriches for […]

Over the past eight years we have a diagnostic test for disease resistance in honey bees and then attempted to use this test to selectively breed disease-resistant bees. The bees selected in this way appear to not lose other economically important traits (e.g., honey production) but are far better equipped to deal with disease than […]

Decreasing operational costs is a key criterion for organizations that manage compute clusters, such as Amazon, Microsoft, Google, Alibaba, etc. One way to decrease costs it to improve resource utilization in the cluster [13, 14]. Yet, high resource utilization can negatively affect workload performance and thus user satisfaction. Performance degradation happens when workloads running on […]

The environmental stress of altitude and heat have both been shown to elicit divergent adaptive responses and are used by elite athletes to augment training adaptation and subsequent performance. Indeed, 3-4 weeks at moderate altitudes can increase the body’s natural erythropoietin (EPO) responses, raising hemoglobin by 4-6% and enhancing endurance performance. Conversely, as little as […]

The environmental stress of altitude and heat have both been shown to elicit divergent adaptive responses and are used by elite athletes to augment training adaptation and subsequent performance. Indeed, 3-4 weeks at moderate altitudes can increase the body’s natural erythropoietin (EPO) responses, raising hemoglobin by 4-6% and enhancing endurance performance. Conversely, as little as […]

In this joint collaboration with BNS, we will develop a behavioural risk model to predict the likelihood of future risk of breaking the promise to pay debt for customers who only hold deposit products with BNS. The model will be utilized to support business operations such as credit card and loan pre-approvals. That is to […]

Fish farms are a way to satisfy the increasing demand for fish without directly impacting wild stocks. In fish farms water quality significantly impacts fish health and development. Industrial fish farms rely on aerators for multiple purposes, including the oxygenation of water and the isolation of fish from plankton blooms. However, at this time, several […]

My proposal directly builds on my Ph.D. work, which has concerned how musical and theatre improvisation can be applied in business and public health settings to promote cognitive and social-cognitive goals. In particular, Lululemon is interested in harnessing the cognitive principles underlying improvisation in order to promote emotional fitness in two complimentary ways––at a human […]

Urban streams are prone to flooding and bank erosion as a result of the large amount of stormwater that is transported into the channel across the paved floodplain. Many streams in urban areas are being restored to a more natural state so that they are able to accommodate flood pulses as well as to increase […]

Rivers naturally shift and move through lateral erosion and deposition, which can cause problems for infrastructure that is built on riverbanks. Traditional engineering solutions have entirely halted lateral movement, which can have negative consequences. This research is investigating an alternative method, which uses grains that are within the grain size distribution of the riverbed, rather […]

Modern molecularly targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute blood cancer patients. This is largely due to the survival of some blood cancer cells that possess unique properties and can cause treatment failure or relapse, highlighting the need for new therapies. In collaboration with […]

I will continue my research on Chinese Buddhism at UBC, with a focus on Tang Buddhist Palace Chapels. The Tang Buddhist palace chapels which are special products of satisfying the royal family’s religious and political needs actually combine religious sanctification and political momentum in the virtue of sacred space, in order to meet the needs […]