Vancouver Foundation (VF)’s Indigenous-led systems change grants support organizations addressing structural inequalities and racism faced by Indigenous organizations in BC. These organizations have historically been marginalized, counted on few resources and spent much of their time reporting to donors and coping with other bureaucratic barriers. This research will bridge the gap by reviewing academic and […]

Machine-to-machine (M2M) user equipments (UEs), which do not require a direct human interaction for communicating to each other, are predicted to have a large end-user market in the near future with numerous potential applications, such as home automation, patient monitoring, transportation, and smart metering. Currently, machine-type communication (MTC) is in the process of being standardized […]

The objective of this project is to develop lipid nanoparticle (LNP) reagents for the delivery of nucleic acids to turn off, or turn on target genes in “hard-to-transfect” neurons and stem cells in vitro and in vivo. A recent report (BCC Research, April 2011) observed that “51% of researchers employ cell-based techniques to perform transfection […]

The objective of this project is to develop lipid nanoparticle (LNP) reagents for the delivery of nucleic acids to turn off, or turn on target genes in “hard-to-transfect” neurons and stem cells in vitro and in vivo. A recent report (BCC Research, April 2011) observed that “51% of researchers employ cell-based techniques to perform transfection […]

The high prevalence of obstructive sleep apnea (OSA) poses a serious threat to the healthy growth and development of many children. The lack of oxygen during sleep can lead to daytime sleepiness, growth failure, behavioural problems and developmental delay. Polysomnography (PSG), the gold standard to diagnose OSA is high in cost, requires a well-equipped sleep […]

The high prevalence of obstructive sleep apnea (OSA) poses a serious threat to the healthy growth and development of many children. The lack of oxygen during sleep can lead to daytime sleepiness, growth failure, behavioural problems and developmental delay. Polysomnography (PSG), the gold standard to diagnose OSA is high in cost, requires a well-equipped sleep […]

Screening with low-dose CT has been shown to significantly reduce lung cancer related mortality in high-risk ever-smokers. Interval cancer (IC) is a rising challenge in lung cancer screening because it usually presents in an advanced stage (stage III/IV non-small cell cancer) or is more biologically aggressive (i.e., small cell histology) and have a poorer prognosis […]

Service robots can offer personalized service for people with disabilities and empower the staff with efficient support. This study investigates using a collaborative service robot, Aether in a long-term care home. We work collaboratively with people living with disabilities, families, frontline staff, operation leaders, and industry) to Identify user experience, impact and challenges to inform […]

Seasonal influenza causes significant mortality and morbidity worldwide, and we are currently unprepared to mitigate a fatal pandemic outbreak like the 1918 Spanish Flu. A proven influenza antiviral target is the M2 viroporin, or viral ion channel. Amantadine, an M2 inhibitor was an effective antiviral for 20 years. However, current influenza antivirals are increasingly ineffective […]

In 2022, over 4.5 billion doses of the Pfizer-BioNTech and the Moderna COVID-19 vaccines were produced to combat a devastating pandemic. The above vaccines contain messenger RNA (“mRNA”) trapped inside lipid nanoparticles (“LNPs”), which are globules with a diameter of a few billionths of a meter, composed of fatty substances called lipids. A crucial type […]

In rock engineering practice there is often insufficient time, schedule, and computational/expert resources to investigate complex rock mass phenomena in detail. The large amount of multivariate data that characterizes complex rock mass behaviour creates the ideal conditions to use machine learning. Machine learning allows for the use of all relevant data and can inform the […]

In 2021, over 2.2 billion doses of the Pfizer-BioNTech and Moderna COVID-19 vaccines were produced to combat a truly devastating pandemic. Such medications represent the fastest vaccines ever to be developed, with some of the highest efficiencies reported. The above vaccines contain messenger RNA (“mRNA”) trapped inside lipid nanoparticles (“LNPs”), which are globules composed of […]